[COMPREHENSIVE GUIDELINES AND INDICATIONS FOR DIGITAL MONITORING OF PATIENTS AT HIGH-RISK FOR MELANOMA: A POSITION PAPER BY THE ISRAELI ASSOCIATION FOR DERMATOLOGY].

Harefuah Pub Date : 2024-04-01
Ofer Reiter, Mor Miodovnik, Emily Avitan-Hersh, Nadav Astman, Nir Nathanson, Ayelet Rishpon, Aviv Barzilai, Alon Scope
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Abstract

Introduction: Early detection may lead to reduced morbidity and mortality from melanoma. This study aims to establish guidelines for selecting patients suitable for digital monitoring of skin lesions.

Methods: A literature review was conducted, followed by consensus among experts appointed by the Israeli Dermatology Association.

Results: Two effective methods for early melanoma diagnosis were identified: Total-body photography (TBP) and digital dermoscopy. TBP involves capturing clinical images of the entire skin area for long-term monitoring (6-12 months). Digital dermoscopy focuses on close-up images of distinct lesions for short-term monitoring (3-4 months). Various risk factors for melanoma were identified, including genetic and familial factors, as well as demographic and phenotypic characteristics. Based on these risk factors and feasibility of clinical follow-up, a comprehensive list of indications for TBP was developed, categorized into three groups based on the expected level of benefit. Digital dermoscopy surveillance is recommended for patients with flat or slightly raised skin lesions showing dermoscopic features that do not definitively indicate melanoma.

Discussion: TBP significantly improves early melanoma detection, enhancing sensitivity and specificity while reducing unnecessary biopsies. However, due to its high cost and limited coverage by the Israeli public health care system, prioritizing patients who would benefit most from TBP is crucial. The compiled list of indications aligns with international recommendations and provides further details within the article.

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[对黑色素瘤高危患者进行数字监测的综合指南和适应症:以色列皮肤病协会立场文件]。
导言:早期发现可降低黑色素瘤的发病率和死亡率。本研究旨在为选择适合进行皮肤病变数字监测的患者制定指导方针:方法:进行文献综述,然后由以色列皮肤病协会任命的专家达成共识:结果:确定了两种早期诊断黑色素瘤的有效方法:结果:确定了两种有效的早期黑色素瘤诊断方法:全身摄影(TBP)和数字皮肤镜检查。全身照相是指捕捉整个皮肤区域的临床图像,进行长期监测(6-12 个月)。数字皮肤镜主要拍摄明显病变的特写图像,用于短期监测(3-4 个月)。已确定黑色素瘤的各种风险因素,包括遗传和家族因素,以及人口和表型特征。根据这些风险因素和临床随访的可行性,制定了一份全面的 TBP 适应症清单,并根据预期获益程度分为三类。对于皮肤平整或轻微隆起,但皮肤镜显示特征不能明确提示黑色素瘤的患者,建议进行数字皮肤镜监测:讨论:TBP 能明显改善早期黑色素瘤的检测,提高灵敏度和特异性,同时减少不必要的活检。然而,由于 TBP 费用高昂,且以色列公共医疗系统的覆盖范围有限,因此优先考虑从 TBP 中获益最多的患者至关重要。所汇编的适应症清单与国际建议一致,并在文章中提供了更多详细信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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