[Post-COVID-19 condition in children and adolescents from a cohort: prevalence and risk factors].

Sergio Iván Assia-Robles, María Del Rocío Hernández-Morales, Eleazar Mancilla-Hernández, Diana Paola López-Méndez, Samara Nazarala-Sanchez, Sandra Aidée González-Hidalgo
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Abstract

Objective: To determine the prevalence and risk factors of the post-COVID-19 condition of children and adolescents from a cohort.

Methods: Observational and analytical cohort study. Statistical analysis: percentages, frequencies; averages; Odds ratio, χ2 test, and multiple binary logistic regression. Statistical Package, for the Social Sciences 23.

Results: Prevalence of the post-COVID-19 condition was: 14.8% of 175 patients who fulfilled the inclusion criteria, 26 developed post-COVID-19 condition, mean age 5.9 years (SD: 5.05), sex: 27% men, 73% women, frequent symptoms: fatigue, runny nose, muscle pain, dyspnea. Symptoms associated with post-COVID-19 condition: muscle pain (OR: 27; p = 0.000; IC95%5.2-139), dysgeusia (OR: 19; p = 0.012; IC95%: 1.9-19), and fatigue (OR: 5; p = 0.001; IC95%: 1.9-13.5). Associated risk factors: female (OR: 3.58; p = 0.023; CI95%: 1.19-10.71), comorbidities (OR: 24.5; p = 0.000; CI95%: 7.52-79), allergic rhinitis (OR: 8.7; p = 0.000; CI95%: 2.66-28.87), atopic dermatitis (OR: 9. 58; p = 0.016 CI95%: 1.51-60.5).

Conclusions: Although the majority of children infected with SARS-CoV-2 recover completely, some of them will develop a post-COVID-19 condition, knowing the most frequent symptoms and associated factors, will allow a better evaluation, for its opportune detection and effective treatment.

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[来自队列的儿童和青少年中的后 COVID-19 症状:发病率和风险因素]。
目的从队列中确定儿童和青少年 COVID-19 后状况的流行率和风险因素:观察和分析队列研究。统计分析:百分比、频率、平均值、比率、χ2 检验和多元二元逻辑回归。采用社会科学统计软件包 23.结果:符合纳入标准的 175 名患者中,COVID-19 后病症的患病率为 14.8%,26 人出现 COVID-19 后病症,平均年龄为 5.9 岁(标清:5.05),性别:27% 为男性,73% 为女性,常见症状:疲劳、流鼻涕、肌肉疼痛、呼吸困难。与 COVID-19 后症状相关的症状:肌肉疼痛(OR:27;P = 0.000;IC95%5.2-139)、呼吸困难(OR:19;P = 0.012;IC95%:1.9-19)和疲劳(OR:5;P = 0.001;IC95%:1.9-13.5)。相关风险因素:女性(OR:3.58;p = 0.023;CI95%:1.19-10.71)、合并症(OR:24.5;p = 0.000;CI95%:7.52-79)、过敏性鼻炎(OR:8.7;p = 0.000;CI95%:2.66-28.87)、特应性皮炎(OR:9.58;p = 0.016 CI95%:1.51-60.5):虽然大多数感染 SARS-CoV-2 的儿童都能完全康复,但其中一些儿童会出现后 COVID-19 症状,了解最常见的症状和相关因素将有助于更好地进行评估,以便及时发现和有效治疗。
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