Antibiotics for Treatment of Chronic Periodontitis, in Conditions of Increased Resistance

Abstract

The study is oriented around the collection of already published data about treatment of chronic periodontitis according to specifics with or without antibiotics, given locally or systemically. Tetracycline and metronidazole, combined or not with amoxicillin according to the clinical indications of the pathology, are the most applied combinations indicated for the treatment of chronic periodontitis. This element is based on the fact that these antibiotics act specifically against the pathogenic bacteria of chronic periodontitis. The study is a review type. The collection of information is oriented around finding the trend of scientific research in this direction, towards how this data is sought through the results of review-type studies, or studies based on experiments performed in vitro or in vivo on teeth affected by this pathology. The preference for antibiotics and how it has evolved during the selected years in this study is another goal in itself for this study, to closely connect it with the evolution of the concept of how this pathology appears and who are its causes. The marketing of different antibiotic manufacturing firms, or the tendency to use combinations of antibiotics and the evaluation of this tendency, is another aim of this study. The electronic research was done in PubMed page, using the keywords according to certain combinations. The search time interval is 5 years, articles published in PubMed about chronic periodontitis, and the treatment of this pathology by means of antibiotics. This study supports the fact that the new trends for treatment of this pathology with or without antibiotics are also oriented towards the application or not of probiotics, knowing that the latters are currently under further exploration and evolution. It is known the fact that we live after the transition phase of COVID-19, where most of the population was treated with azithromycin, an antibiotic usually recommended for treatment of periodontal pathologies, as it appears “with the ability” to pour directly into the gingival fluid.