Primary Extraskeletal Falcine Myxoid Chondrosarcoma—A Case Report and Review of Literature

Rajasekhar Narayanan, Renjith T. Venugopal, Suresh Kumar K. L., Jose P. B., Anjana Bahuleyan, Reshmi C. P., Thomas Varghese, Marthanda A Pillai
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Abstract

Intracranial chondrosarcomas are rare malignant lesions. Both skull base and dural-based extraosseous chondrosarcomas have been reported to occur intracranially. Dural-based chondrosarcomas arising from the falx cerebri are rare lesions with only 19 cases reported till date. Although conventional, mesenchymal, and myxoid variants of chondrosarcomas have been reported intracranially, myxoid variant are the rarest with only 17 cases reported till date, among which only 2 were falcine. We are reporting the third case of falcine myxoid chondrosarcoma in a 32-year-old man who presented with seizures and subtle lower limb weakness. Radiological findings were suggestive of an atypical meningioma in the falcine region. Macroscopically total resection of the tumor was done. Histopathological examination confirmed myxoid chondrosarcoma, grade 1. Postoperative period was uneventful, and the patient remains asymptomatic 34 months after the surgery without the application of any adjuvant therapy. Falcine myxoid chondrosarcomas are extremely rare lesions with variable aggressiveness as suggested by the three cases reported till now including the present case.
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原发性骨外法尔兹肌样软骨肉瘤--病例报告和文献综述
颅内软骨肉瘤是一种罕见的恶性病变。据报道,颅底和硬脑膜外软骨肉瘤均可发生于颅内。发生于大脑镰的硬脑膜外软骨肉瘤是罕见病变,迄今仅有19例报道。虽然颅内软骨肉瘤的传统型、间充质型和类肉瘤变体均有报道,但类肉瘤变体最为罕见,迄今仅有17例报道,其中仅2例为镰状。我们报告的是第三例镰刀状肌样软骨肉瘤,患者为一名 32 岁男子,出现癫痫发作和下肢无力。放射学检查结果提示为镰状区域的非典型脑膜瘤。医生在显微镜下对肿瘤进行了全切除。组织病理学检查证实为肌样软骨肉瘤,1级。患者术后恢复顺利,术后34个月仍无症状,未进行任何辅助治疗。迄今为止,包括本病例在内的三例报告表明,法尔金肌样软骨肉瘤是一种极其罕见的病变,具有不同的侵袭性。
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