Elranatamab treatment in a multiple myeloma patient undergoing renal dialysis

Zoé Van de Wyngaert, Irene Romera-Martinez, Céline Chedeville, Paolo Musiu, Souhila Ikhlef, Bénédicte Jonca, M. Mohty, F. Malard
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Abstract

We present the case of a dialyzed patient with relapsed IgA and lambda free light chain multiple myeloma treated with elranatamab. Despite end-stage renal impairment, the treatment with anti-B cell maturation antigen (BCMA)xCD3 bispecific antibody proved to be feasible, without unexpected side effects. Increased attention to infectious risk is crucial for these doubly fragile patients.
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接受肾透析的多发性骨髓瘤患者的艾拉他单抗治疗
我们介绍了一例使用艾拉他单抗治疗复发的IgA和游离λ轻链多发性骨髓瘤透析患者的病例。尽管患者处于终末期肾功能损害,但使用抗B细胞成熟抗原(BCMA)xCD3双特异性抗体进行治疗证明是可行的,而且没有出现意外的副作用。对于这些双重脆弱的患者来说,加强对感染风险的关注至关重要。
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