In silico evidence that substitution of glycine for valine (p.G8V) in a common variant of TMPRSS2 isoform 1 increases accessibility to an endocytic signal: implication for SARS-CoV-2 entry into host cells and susceptibility to COVID-19.
Matteo Calcagnile, F. Damiano, G. Lobreglio, L. Siculella, M. Bozzetti, Patricia Forgez, Alexandra Malgoyre, Nicolas Libert, Cecilia Bucci, Marco Alifano, Pietro Alifano
{"title":"In silico evidence that substitution of glycine for valine (p.G8V) in a common variant of TMPRSS2 isoform 1 increases accessibility to an endocytic signal: implication for SARS-CoV-2 entry into host cells and susceptibility to COVID-19.","authors":"Matteo Calcagnile, F. Damiano, G. Lobreglio, L. Siculella, M. Bozzetti, Patricia Forgez, Alexandra Malgoyre, Nicolas Libert, Cecilia Bucci, Marco Alifano, Pietro Alifano","doi":"10.1016/j.biochi.2024.05.004","DOIUrl":null,"url":null,"abstract":"","PeriodicalId":3,"journal":{"name":"ACS Applied Electronic Materials","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Electronic Materials","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1016/j.biochi.2024.05.004","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}