Nakita O’Rourke, Ross Haverty, Arlene Mannion, Sally Whelan, Geraldine Leader
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引用次数: 0
Abstract
Studies have reported high prevalence rates of sleep problems in Angelman Syndrome (AS), relating to abnormal sleep–wake cycles and reduced sleep duration. This systematic review aimed to characterise sleep problems in AS, investigate how they are assessed and identify the treatments/interventions prescribed. A systematic search of PsycINFO, PubMed and Psychology & Behavioral Sciences Collection was conducted using pre-determined search terms. Relevant studies published between 2016 and mid-2020 were included to expand on earlier reviews. Seven articles quantifying sleep problems, assessment and treatment/intervention in children and adults with AS were reviewed (N = 266). Findings demonstrated reduced total sleep duration (M = 538 min), longer night-awakenings (M = 67 min) and reduced sleep efficiency (78%) in AS compared with typically developing peers. Medication was highly prescribed historically/currently (n = 176, 66.2%). This review highlights the clinically significant presence of sleep problems with the majority of individuals requiring medical intervention. Decreased sleep duration, sleep efficiency and increased night-awakenings represent the most significant sleep problems across studies. Findings suggest sleep problems begin in infancy but improve in adulthood. This finding should be considered with caution as only two studies included an adult sample. Priorities for future research should focus on longitudinal studies to determine whether sleep problems improve with age in AS.
期刊介绍:
The Review Journal of Autism and Developmental Disorders publishes original articles that provide critical reviews of topics across the broad interdisciplinary research fields of autism spectrum disorders. Topics range from basic to applied and include but are not limited to genetics, neuroscience, diagnosis, applied behavior analysis, psychopharmacology, incidence, prevalence, etiology, differential diagnosis, treatment, measurement of treatment effects, education, perception and cognition. Topics across the life span are appropriate. In addition, given the high rates of comorbid conditions, the interface of sleep disorders, feeding problems, motor difficulties, ADHD, anxiety, depression and other disorders with autism spectrum disorders are appropriate. The Journal aims for an international audience as reflected in the editorial board.