Summary Document Research on RDS Anti-addiction Modeling: Annotated Bibliography.

Journal of addiction psychiatry Pub Date : 2024-04-05
Kenneth Blum, David Baron, Thomas McLaughlin, Panayotis K Thanos, Catherine Dennen, Mauro Ceccanti, Eric R Braverman, Alireza Sharafshah, Kai-Uwe Lewandrowski, John Giordano, Rajendra D Badgaiyan
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Abstract

Annotated bibliography of genetic addiction risk severity (GARS) publications, pro-dopamine regulation in nutraceuticals (KB220 nutraceutical variants), and policy documents. Further research is required to encourage the field to consider "Reward Deficiency Syndrome (RDS) Anti-addiction Modeling" which involves early risk identification by means of genetic assessment similar to GARS, followed by induction of dopamine homeostasis by means of genetically guided pro-dopamine regulation similar to KB220. These results suggest that genetically based treatments may be a missing piece in the treatment of substance use disorder (SUD).

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RDS 防沉迷模型研究摘要文件:附加说明的参考书目。
附加说明的遗传成瘾风险严重程度(GARS)出版物书目、营养保健品(KB220 营养保健品变体)中的促多巴胺调节以及政策文件。需要进一步开展研究,以鼓励该领域考虑 "奖赏缺失综合征(RDS)抗瘾模型",该模型涉及通过类似于 GARS 的基因评估手段进行早期风险识别,然后通过类似于 KB220 的基因引导的促多巴胺调节手段诱导多巴胺稳态。这些结果表明,基于基因的治疗方法可能是治疗药物使用障碍(SUD)的一个缺失环节。
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Summary Document Research on RDS Anti-addiction Modeling: Annotated Bibliography. Is There a Natural, Non-addictive, and Non-anti-reward, Safe, Gene-based Solution to Treat Reward Deficiency Syndrome? KB220 Variants vs GLP-1 Analogs. Solving the Global Opioid Crisis: Incorporating Genetic Addiction Risk Assessment with Personalized Dopaminergic Homeostatic Therapy and Awareness Integration Therapy. Theorizing that Psychedelic Assisted Therapy May Play a Role in the Treatment of Trauma-Induced Personality Disorders. Psychostimulants for Children: Are We Over or Under Dosing?
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