Use of Complementary and Alternative Medicine in Patients With Idiopathic Inflammatory Demyelinating Diseases of the Central Nervous System: A Cross-Sectional Study in Thailand

IF 1.5 Q3 MEDICINE, RESEARCH & EXPERIMENTAL Current Therapeutic Research-clinical and Experimental Pub Date : 2024-01-01 DOI:10.1016/j.curtheres.2024.100749

Punchika Kosiyakul MD , Jiraporn Jitprapaikulsan MD , Natthapon Rattanathamsakul MD , Sasitorn Siritho MD , Onpawee Sangsai MSc , Kamonchanok Aueaphatthanawong BSc , Montira Engchuan BNS , Naraporn Prayoonwiwat MD

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Abstract

Background

Complementary and alternative medications (CAM) are common among patients with multiple sclerosis (MS) for physical and psychological support. However, there is insufficient data regarding the application of CAM in the different cultures and beliefs of each community as well as patient's status.

Objective

To evaluate the prevalence and modalities of the use of CAM among patients with central nervous system idiopathic inflammatory demyelinating diseases (CNS-IIDD) in a tertiary care hospital

Methods

A cross-sectional study was conducted at Siriraj Hospital from June to December 2021 involving patients with MS, neuromyelitis optic spectrum disorders (NMOSD), myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), idiopathic transverse myelitis (iTM), and optic neuritis (ON) to examine the prevalence and mode of CAM use and its correlation with patient characteristics.

Results

There were 107 patients. The diagnoses were MS (38), NMOSD (55), MOGAD (5), iTM (7), and ON (2). Most of the patients were female (89.7%), and 61.7% were diagnosed over 5 years. The mean Expanded Disability Status Scale was 2.63 (S.D., 2.38), and the median ambulation index was 0 (range 0–8.5). There were 68 patients (63.6%) with a history of CAM use for at least 3 months, while those with current use decreased to 62 (58.5%). Vitamins and minerals were the most commonly used, particularly vitamin D (97.1%) and calcium (47.7%). Both treatments were primarily prescribed (95.3%) rather than self-administered (24.3%). The main reasons for the use of CAM were to strengthen their health (48.6%) and relieve existing symptoms (28.0%).

Conclusions

The use of CAM is common among patients with Thai CNS-IIDD. Further exploration of patient perspectives and preferences regarding CAM usage may contribute to a more comprehensive management approach for patients with CNS-IIDD.

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中枢神经系统特发性炎症性脱髓鞘疾病患者使用补充和替代医学的情况：泰国横断面研究

背景在多发性硬化症（MS）患者中，补充和替代药物（CAM）是一种常见的生理和心理支持疗法。然而，有关 CAM 在不同文化、不同社区信仰以及不同患者状况下的应用情况的数据尚不充分。方法2021年6月至12月，在Siriraj医院开展了一项横断面研究，涉及多发性硬化症患者、神经脊髓炎视神经谱系障碍（NMOSD）、髓鞘少突胶质细胞糖蛋白抗体相关疾病（MOGAD）、特发性横贯性脊髓炎（iTM）和视神经炎（ON）患者进行了横断面研究，以了解 CAM 的使用率和方式及其与患者特征的相关性。结果共有 107 名患者。诊断为多发性硬化症（38 例）、非弥漫性横贯性肌病（55 例）、MOGAD（5 例）、iTM（7 例）和视神经炎（2 例）。大多数患者为女性（89.7%），61.7%的患者确诊时间超过 5 年。残疾状况扩展量表》（Expanded Disability Status Scale）的平均值为 2.63（S.D. ，2.38），行走指数中位数为 0（范围 0-8.5）。有 68 名患者（63.6%）使用过至少 3 个月的 CAM，而目前使用 CAM 的患者减少到 62 名（58.5%）。维生素和矿物质是最常用的药物，尤其是维生素 D（97.1%）和钙（47.7%）。这两种治疗方法主要是处方药（95.3%），而不是自用药（24.3%）。使用 CAM 的主要原因是为了增强体质（48.6%）和缓解现有症状（28.0%）。进一步探讨患者使用 CAM 的观点和偏好可能有助于为中枢神经系统-IIDD 患者提供更全面的管理方法。

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来源期刊

Current Therapeutic Research-clinical and Experimental 医学-药学

CiteScore

3.50

自引率

0.00%

发文量

审稿时长

3 months

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