Recurrent unilateral facial nerve palsy in acute lymphocytic leukaemia.

IF 2.4 Q2 CLINICAL NEUROLOGY PRACTICAL NEUROLOGY Pub Date : 2024-11-17 DOI:10.1136/pn-2024-004175
Robert Kassinger, Amir Adeli
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Abstract

A man in his mid-20s developed three episodes of right facial weakness over 5 months. He had a history of B-cell acute lymphoblastic leukaemia (ALL) in remission following allogenic stem cell transplantation. MR scan of brain during the second presentation showed facial nerve enhancement; cerebrospinal fluid (CSF) cytology and flow cytometry were negative. Re-assessment at the third presentation identified CSF B-lymphoblasts, and he was subsequently treated for central nervous system relapse of leukaemia. This case highlights an infrequent presenting symptom of ALL relapse and a rare cause of recurrent facial nerve palsy.

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急性淋巴细胞白血病复发性单侧面神经麻痹。
一名 20 多岁的男子在 5 个月内出现了三次右侧面部无力的症状。他曾患B细胞急性淋巴细胞白血病(ALL),异基因干细胞移植后病情缓解。第二次发病时,脑部核磁共振扫描显示面神经增强;脑脊液(CSF)细胞学检查和流式细胞术检查均为阴性。第三次就诊时再次评估发现脑脊液中存在B淋巴细胞,随后他因中枢神经系统白血病复发接受了治疗。本病例强调了白血病复发的一个不常见症状,以及导致面神经复发性麻痹的一个罕见病因。
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来源期刊
PRACTICAL NEUROLOGY
PRACTICAL NEUROLOGY Medicine-Neurology (clinical)
CiteScore
3.70
自引率
3.60%
发文量
113
期刊介绍: The essential point of Practical Neurology is that it is practical in the sense of being useful for everyone who sees neurological patients and who wants to keep up to date, and safe, in managing them. In other words this is a journal for jobbing neurologists - which most of us are for at least part of our time - who plough through the tension headaches and funny turns week in and week out. Primary research literature potentially relevant to routine clinical practice is far too much for any neurologist to read, let alone understand, critically appraise and assimilate. Therefore, if research is to influence clinical practice appropriately and quickly it has to be digested and provided to neurologists in an informative and convenient way.
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