A method for determining groups in cumulative incidence curves in competing risk data

IF 1.3 3区 生物学 Q4 MATHEMATICAL & COMPUTATIONAL BIOLOGY Biometrical Journal Pub Date : 2024-05-22 DOI:10.1002/bimj.202300084
Marta Sestelo, Luís Meira-Machado, Nora M. Villanueva, Javier Roca-Pardiñas
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Abstract

The cumulative incidence function is the standard method for estimating the marginal probability of a given event in the presence of competing risks. One basic but important goal in the analysis of competing risk data is the comparison of these curves, for which limited literature exists. We proposed a new procedure that lets us not only test the equality of these curves but also group them if they are not equal. The proposed method allows determining the composition of the groups as well as an automatic selection of their number. Simulation studies show the good numerical behavior of the proposed methods for finite sample size. The applicability of the proposed method is illustrated using real data.

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在竞争风险数据的累积发病率曲线中确定组别的方法。
累积发生率函数是在存在竞争风险的情况下估算特定事件边际概率的标准方法。分析竞争风险数据的一个基本但重要的目标是比较这些曲线,但这方面的文献有限。我们提出了一种新的程序,不仅可以检验这些曲线是否相等,还可以在不相等的情况下对它们进行分组。所提出的方法可以确定组的组成,并自动选择组的数量。模拟研究表明,在样本数量有限的情况下,所提出的方法具有良好的数值表现。使用真实数据说明了所提方法的适用性。
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来源期刊
Biometrical Journal
Biometrical Journal 生物-数学与计算生物学
CiteScore
3.20
自引率
5.90%
发文量
119
审稿时长
6-12 weeks
期刊介绍: Biometrical Journal publishes papers on statistical methods and their applications in life sciences including medicine, environmental sciences and agriculture. Methodological developments should be motivated by an interesting and relevant problem from these areas. Ideally the manuscript should include a description of the problem and a section detailing the application of the new methodology to the problem. Case studies, review articles and letters to the editors are also welcome. Papers containing only extensive mathematical theory are not suitable for publication in Biometrical Journal.
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