[Unusual progression of polycythemia vera].

Innere Medizin (Heidelberg, Germany) Pub Date : 2024-10-01 Epub Date: 2024-05-22 DOI:10.1007/s00108-024-01714-2
Philipp Lohneis, Heinz-Wolfram Bernd, Peter Czyborra
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Abstract

The case of a male patient with newly diagnosed polycythemia vera showing rare and unusually rapid progression with phenotypic change towards chronic myelomonocytic leukemia is presented. The case report illustrates remarkably rapid disease progression including a structural change in usually indolent polycythemia vera and highlights the prognostic relevance of enhanced molecular genetic testing.

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[多发性红细胞症的不寻常进展]。
本病例涉及一名新确诊的男性多发性红细胞症患者,该患者的病情进展罕见且异常迅速,表型向慢性粒细胞白血病转变。该病例报告说明了疾病进展异常迅速,包括通常为轻度多发性红细胞症的结构改变,并强调了加强分子基因检测对预后的意义。
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