Lili Wen , Qiannan Tan , Chao Pi , Juan Yuan , Jingyu Zhang , Xia Mi
{"title":"Visible-light-mediated C–H amidation of imidazoheterocycles with N-amidopyridiniums†","authors":"Lili Wen , Qiannan Tan , Chao Pi , Juan Yuan , Jingyu Zhang , Xia Mi","doi":"10.1039/d4ob00461b","DOIUrl":null,"url":null,"abstract":"<div><p>C-3 amidated imidazoheterocycles were synthesized <em>via</em> a visible light-promoted reaction of imidazoheterocycles with <em>N</em>-amidopyridinium salts catalyzed by 4CzIPN under mild conditions. For imidazoheterocycles and <em>N</em>-amidopyridinium salts with various substituents, the reaction proceeded smoothly to give the corresponding products in moderate to good yields. The reaction provides a new strategy for the synthesis of secondary amides with the imidazo[1,2-<em>a</em>]pyridine core.</p></div>","PeriodicalId":96,"journal":{"name":"Organic & Biomolecular Chemistry","volume":null,"pages":null},"PeriodicalIF":2.9000,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic & Biomolecular Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1477052024004646","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
C-3 amidated imidazoheterocycles were synthesized via a visible light-promoted reaction of imidazoheterocycles with N-amidopyridinium salts catalyzed by 4CzIPN under mild conditions. For imidazoheterocycles and N-amidopyridinium salts with various substituents, the reaction proceeded smoothly to give the corresponding products in moderate to good yields. The reaction provides a new strategy for the synthesis of secondary amides with the imidazo[1,2-a]pyridine core.