UNLOCKING THE LINK: DENGUE SEROLOGICAL MARKER AND PLATELET DYNAMICS

International journal of scientific research Pub Date : 2024-05-01 DOI:10.36106/ijsr/3408101

Prakash Narayan Gupta, Bhagya Babu

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Abstract

Background: Dengue a vector borne disease considered hazard to public health. Diagnosis is by dengue specic antigen and antibody detection. Decrease in platelet count consider as warning sign in dengue positive cases. Hence this study was done to correlate various dengue parameter and platelet count. Material and Methods: A Retrospective analytical study conducted from period of September 2022- September 2023.A total of 1670 serum samples tested for dengue using ICTkit , 82 samples were tested positive. Platelet count recorded for all the cases. Results: 1670 serum sample tested for dengue, 82 sample tested positive for dengue antigen or antibody by ICT based test. Thrombocytopenia (platelet count < 100,000/ml) observed in 20 cases. Association of thrombocytopenia in dengue positive cases was more signicant as compared to dengue negative cases. Conclusion: A necessary to provide association of thrombocytopenia and various dengue markers to physician in management of dengue infection, which further help in reducing complications as thrombocytopenia association in dengue case was signicant as compared to other dengue negative cases.

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解开联系：登革热血清学标记与血小板动力学

背景：登革热是一种病媒传染的疾病，被认为危害公众健康。诊断方法是检测登革热特异c 抗原和抗体。血小板计数减少被认为是登革热阳性病例的警示信号。因此，本研究将登革热的各种参数与血小板计数联系起来。材料与方法使用 ICTkit 对 1670 份血清样本进行登革热检测，其中 82 份样本检测结果呈阳性。记录了所有病例的血小板计数。结果1670 份血清样本进行了登革热检测，其中 82 份样本的登革热抗原或抗体检测呈阳性。在 20 个病例中观察到血小板减少（血小板计数<100,000/ml）。与登革热阴性病例相比，登革热阳性病例中血小板减少症的相关性更为显著。结论：有必要向医生提供血小板减少与登革热感染管理中的各种登革热标志物之间的关联，这将进一步帮助减少并发症，因为与其他登革热阴性病例相比，登革热病例中血小板减少与登革热阴性病例之间的关联更为显著。

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International journal of scientific research

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