A STUDY ON THE ASSOCIATION OF DRY EYE WITH DYSLIPIDEMIA

Abstract

Aim: This study investigates the association of dry eye disease (DED) with dyslipidemia. The study also assessed the association of visual display terminal (VDT) and DED in patients with dyslipidemia. The meibomian gland dysfunction (MGD) in DED in patients with dyslipidemia was also studied. In the OPD, 60 patients aged 20-60 years with dyslipidemia were studied. After obtaining i Methods: nformed consent, medical history, and direct interviews using a questionnaire, emphasis was placed on dry eye history before applying the DEEP score. Assessments included VDT use, visual acuity, slit lamp examination for ocular allergy signs, and meibomian gland dysfunction degree. Diagnostic tests (Tear break up time (tBUT), Fluorescein staining, Schirmer's test) determined dry eye grading. Patients were categorized by gender and dry eye status. Serum lipid levels were analyzed to establish the dyslipidemia-DED association. Dyslipidemia criteria included elevated cholesterol, triglycerides, low-density lipoprotein (LDL), and low high-density lipoprotein (HDL) levels. In women, a signicant associatio Results And Findings: n exists between DED and dyslipidemia (p < 0.001), with total cholesterol showing notable relevance, particularly in women. The correlation between dyslipidemia and DED is more prominent among women than men. There was a major difference between the VDT usage in patients with and without DED. Additionally, a substantial difference in MGD is evident between DED and non-DED patients (p = 0.001). Findings reveal a robust Conclusion: association between DED progression and dyslipidemia in women. Patient education on dry eye and ophthalmologists diagnosing dyslipidemia can prevent blindness and cardiovascular disease. t-BUT is affected signicantly among VDT users shows that tear lm becomes unstable by their usage, hence helps in nding the actual correlation of dry eye with the use of VDT. MGD demonstrates statistical signicance (p = 0.001), leading to tear lm alterations, eye irritation, inammation, and ocular surface disease.