Daniel J. Stokes , Nicholas A. Felan , Kade S. McQuivey , Beau M. McGinley , Rachel M. Frank
{"title":"Biologics Approaches—When, Why, and How?","authors":"Daniel J. Stokes , Nicholas A. Felan , Kade S. McQuivey , Beau M. McGinley , Rachel M. Frank","doi":"10.1016/j.otsm.2024.151082","DOIUrl":null,"url":null,"abstract":"<div><p>Orthobiologics are being investigated to treat a variety of sports medicine pathologies. This article provides an evidence-based approach summarizing currently available options, including viscosupplementation, platelet-rich plasma, bone marrow aspirate concentration, adipose-derived mesenchymal stem cells, and amniotic-derived mesenchymal stem cells. Orthobiologic use in clinical practice necessitates an understanding of the indications, supporting evidence, risks, and benefits. It should maintain a safe, cost-effective, and resource-conscious approach while adhering to regulatory guidelines. This article provides a foundation for understanding when, why, and how to implement orthobiologics.</p></div>","PeriodicalId":54678,"journal":{"name":"Operative Techniques in Sports Medicine","volume":"32 2","pages":"Article 151082"},"PeriodicalIF":0.4000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Operative Techniques in Sports Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1060187224000236","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"SPORT SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Orthobiologics are being investigated to treat a variety of sports medicine pathologies. This article provides an evidence-based approach summarizing currently available options, including viscosupplementation, platelet-rich plasma, bone marrow aspirate concentration, adipose-derived mesenchymal stem cells, and amniotic-derived mesenchymal stem cells. Orthobiologic use in clinical practice necessitates an understanding of the indications, supporting evidence, risks, and benefits. It should maintain a safe, cost-effective, and resource-conscious approach while adhering to regulatory guidelines. This article provides a foundation for understanding when, why, and how to implement orthobiologics.
期刊介绍：
Operative Techniques in Sports Medicine combines the authority of a textbook, the usefulness of a color atlas and the timeliness of a journal. Each issue focuses on a single clinical condition, offering several different management approaches. It''s the easiest way for practitioners to stay informed of the latest surgical advancements and developments.
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