Deep anterior lamellar keratoplasty in advanced keratoconus in children: A 4-year study

B. Preethi, K. Kiran Kumar, N. Malepati
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Abstract

The purpose of the study was to evaluate the outcomes of deep anterior lamellar keratoplasty (DALK) in children and adolescents with advanced keratoconus (KC) at a tertiary eye care center in India. This was a retrospective cross-sectional study. All cases of KC under the age group of 18 years, operated for DALK at a tertiary eye care center in South India, were evaluated from January 2018 to January 2022; outcome measures were best-corrected visual acuity (BCVA), graft clarity at final follow-up, and complications. Of 27 eyes of 25 cases, 16 were male and 9 were female, with a mean age of presentation at 14.9 years. In stromal dissection technique, big bubble was attempted in 23 eyes and achieved in 20 eyes; manual dissection was done for the rest of the cases. Final BCVA varied from 0.1 to 0.6 logMAR units. Twenty-three eyes had excellent graft clarity at final follow-up. Complications noted in the study were intraoperative microperforation in four cases, postoperatively suture-related complications in three cases, and corneal graft rejection in one case. DALK in pediatric age group for advanced KC is an effective treatment option.
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深前板层角膜移植术治疗晚期儿童角膜炎:为期 4 年的研究
本研究旨在评估印度一家三级眼科医疗中心对患有晚期角膜炎(KC)的儿童和青少年实施深前板层角膜移植术(DALK)的效果。 这是一项回顾性横断面研究。 2018年1月至2022年1月期间,印度南部一家三级眼科医疗中心对所有18岁以下接受DALK手术的KC病例进行了评估;结果指标为最佳矫正视力(BCVA)、最终随访时的移植物清晰度和并发症。 25例患者的27只眼睛中,16只为男性,9只为女性,平均发病年龄为14.9岁。在基质剥离技术方面,有23只眼睛尝试了大气泡剥离,20只眼睛实现了大气泡剥离;其余病例则采用了人工剥离。最终的 BCVA 变化范围为 0.1 至 0.6 logMAR 单位。23只眼睛在最终随访时移植物清晰度极佳。研究中发现的并发症有四例为术中微孔,三例为术后缝合相关并发症,一例为角膜移植物排斥。 在晚期 KC 的儿童年龄组中,DALK 是一种有效的治疗方法。
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31
审稿时长
27 weeks
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