Observation of Unexplained Cases of Unilateral Upper Eyelid Retraction from Idiopathic Inflammation or an Atypical Form of Graves' Orbitopathy.

IF 0.8 4区医学 Q4 OPHTHALMOLOGY Klinische Monatsblatter fur Augenheilkunde Pub Date : 2024-05-27 DOI:10.1055/a-2307-0256

Anna Schuh, Katharina Bayerl-Löhe, Christoph Hintschich

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Abstract

Background: We observed cases of unilateral upper eyelid retraction (UER) with unclear pathogenesis, where a definitive diagnosis of Graves' orbitopathy (GO) could not be made and other pathologies were ruled out. The aim is to present patients' findings, discuss possible underlying mechanisms, and to describe diagnostic testing and therapeutic approaches.

Patients and methods: Patients were retrospectively analyzed who presented to the Department of Ophthalmology of LMU Munich between 2016 and 2021 without a definitive diagnosis of GO or other pathological causes.

Results: Thirteen patients with unexplained UER were included; all showed thickening of the levator complex in imaging. When biopsy was performed, no malignancy could be detected. Therapeutic strategies included oral steroids and surgical upper eyelid blepharotomy.

Conclusion: As regards to pathogenesis, in 7/13 patients, a condition of idiopathic UER due to an idiopathic inflammatory response can be postulated rather than a variant of GO.

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观察特发性炎症或非典型性巴塞杜氏眼眶病引起的单侧上眼睑后缩的不明原因病例。

背景：我们观察了一些发病机制不明的单侧上眼睑回缩（UER）病例，这些病例无法明确诊断为巴塞杜氏眼眶病（GO），但排除了其他病因。本文旨在介绍患者的研究结果，讨论可能的潜在机制，并介绍诊断测试和治疗方法：回顾性分析了2016年至2021年期间在慕尼黑大学眼科就诊但未明确诊断为GO或其他病理原因的患者：结果：共纳入13例不明原因的UER患者；所有患者的影像学检查均显示提上睑肌复合体增厚。在进行活组织检查时，未发现恶性肿瘤。治疗策略包括口服类固醇和上眼睑切开术：关于发病机制，可以推测7/13例患者是由于特发性炎症反应引起的特发性UER，而不是GO的变异型。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Klinische Monatsblatter fur Augenheilkunde 医学-眼科学

CiteScore

1.30

自引率

0.00%

发文量

235

审稿时长

4-8 weeks

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