Assessing the usefulness of tubomanometry as a diagnostic tool in Eustachian tube dysfunction.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-10-01 Epub Date: 2024-05-29 DOI:10.1007/s00405-024-08724-8

Mayte Herrera, Estefanía Miranda, Ithzel Villarreal, Teresa Crespo, Guillermo Plaza

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Abstract

Purpose: This study aims to evaluate the validity and reliability of tubomanometry (TMM) in diagnosing obstructive Eustachian tube dysfunction (OETD) before balloon Eustachian tuboplasty (BET).

Methods: A prospective cohort study was conducted, involving 25 patients with sinonasal pathology, 75 patients with middle ear disease, and 25 healthy subjects, totaling 250 ears. All participants underwent comprehensive physical examinations, including TMM, nasal videoendoscopy, otoendoscopy, Valsalva maneuver (VM), tympanometry, and audiometry. Additionally, various scales such as ETDQ-7 and ETS-7 were employed. Tympanometry served as the gold standard for assessing OETD, and comparisons were made among the measures across the three groups.

Results: Among the 125 participants, 44.8% (n = 56) were female, and 55.2% (n = 69) were male, with ages ranging from 19 to 93 years (M = 48.5; SD = 15.6). In our study, VM demonstrated high sensitivity (86.3%) when tympanometry was considered the gold standard. Conversely, TMM, ETDQ-7, and ETS-7 exhibited high specificity, with ETDQ-7 showing the highest specificity (87.4%). Regarding TMM, all R values in patients within the middle ear disease group were pathological (R > 1).

Conclusion: TMM has exhibited notable specificity as a diagnostic tool compared to tympanogram and VM. Nonetheless, the combination of TMM and ETDQ-7 has enabled us to conduct a diagnostic assessment with high sensitivity and specificity for chronic OETD diagnosis.

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评估测管法作为咽鼓管功能障碍诊断工具的实用性。

目的：本研究旨在评估咽鼓管球囊成形术（BET）前使用咽鼓管测量法（TMM）诊断阻塞性咽鼓管功能障碍（OETD）的有效性和可靠性：我们进行了一项前瞻性队列研究，其中包括 25 名鼻窦病变患者、75 名中耳疾病患者和 25 名健康受试者，共计 250 耳。所有参与者都接受了全面的身体检查，包括TMM、鼻腔视频内窥镜检查、耳内窥镜检查、瓦尔萨尔瓦手法（VM）、鼓室测量和听力测量。此外，还采用了各种量表，如 ETDQ-7 和 ETS-7。鼓室测听是评估耳聋的金标准，并对三组的测量结果进行了比较：在 125 名参与者中，44.8%（n = 56）为女性，55.2%（n = 69）为男性，年龄从 19 岁到 93 岁（M = 48.5；SD = 15.6）不等。在我们的研究中，当鼓室测压法被视为金标准时，VM 表现出很高的灵敏度（86.3%）。相反，TMM、ETDQ-7 和 ETS-7 则表现出较高的特异性，其中 ETDQ-7 的特异性最高（87.4%）。关于 TMM，中耳疾病组患者的所有 R 值均为病理值（R > 1）：结论：与鼓室造影和VM相比，TMM作为诊断工具具有显著的特异性。尽管如此，TMM 和 ETDQ-7 的结合使我们能够对慢性中耳炎的诊断进行高敏感性和高特异性的诊断评估。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.

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