Bogdan R. Brutiu, Le Tang, Daniel Kaiser, Nuno Maulide
{"title":"Tetrahydropyran synthesis mediated by catalytic triflic acid and hexafluoroisopropanol","authors":"Bogdan R. Brutiu, Le Tang, Daniel Kaiser, Nuno Maulide","doi":"10.1007/s00706-024-03214-3","DOIUrl":null,"url":null,"abstract":"<p>A Brønsted acid-catalyzed regioselective intramolecular hydroalkoxylation is described. This reaction proceeds via a carbocation intermediate and enables the preparation of 1,1,1’-trisubstituted tetrahydropyran derivatives under mild conditions using catalytic triflic acid (TfOH) and hexafluoroisopropanol (HFIP) as a mediator.</p><h3 data-test=\"abstract-sub-heading\">Graphical abstract</h3>\n","PeriodicalId":19011,"journal":{"name":"Monatshefte für Chemie / Chemical Monthly","volume":"68 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Monatshefte für Chemie / Chemical Monthly","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00706-024-03214-3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A Brønsted acid-catalyzed regioselective intramolecular hydroalkoxylation is described. This reaction proceeds via a carbocation intermediate and enables the preparation of 1,1,1’-trisubstituted tetrahydropyran derivatives under mild conditions using catalytic triflic acid (TfOH) and hexafluoroisopropanol (HFIP) as a mediator.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
