Jelte Kelchtermans, Michael E. March, Frank Mentch, Yichuan Liu, Kenny Nguyen, Hakon Hakonarson
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Abstract
Background The relationship between ambient air pollution (AAP) exposure and asthma exacerbations is well-established. However, mitigation efforts have yielded mixed results, potentially due to genetic variability in the response to AAP. We hypothesize that common single nucleotide polymorphisms (SNPs) are linked to AAP sensitivity and test this through a Genome Wide Association Study (GWAS).
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