Short-term use of an Impella ventricular assist device sterile water-based bicarbonate purge solution for positron emission tomography scanning.

IF 2.1 4区 医学 Q3 PHARMACOLOGY & PHARMACY American Journal of Health-System Pharmacy Pub Date : 2024-10-23 DOI:10.1093/ajhp/zxae160
Sarah M Schumacher, Ryan A Hobbs
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引用次数: 0

Abstract

Purpose: Impella microaxial ventricular assist devices require a dextrose-based purge solution in combination with heparin or sodium bicarbonate to prevent device dysfunction and stoppage, but the dextrose in these solutions can interfere with positron emission tomography (PET) scans, necessitating an alternative approach.

Summary: We describe the short-term use in 2 cases of an alternative purge solution for patients with an Impella 5.5 ventricular assist device undergoing PET scans to rule out infection and malignancy. Sodium chloride solutions cannot be used with Impella ventricular assist devices even for short periods of time due to the potential for motor corrosion. We therefore selected a sterile water-based sodium bicarbonate purge solution, incorporating a short dextrose-free period before and during the PET scan. Imaging was successfully performed with this alternative solution, with monitoring of Impella performance levels and purge parameters throughout the procedure indicating no adverse effects on pump function.

Conclusion: Our sterile water-based bicarbonate purge solution coupled with a short-term restriction of dextrose is a practical option for PET imaging in patients with an Impella ventricular assist device.

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在正电子发射断层扫描中短期使用 Impella 心室辅助装置无菌水基碳酸氢盐清洗液。
免责声明:为了加快文章的出版速度,AJHP在接受稿件后会尽快在网上发布。被录用的稿件已经过同行评审和校对,但在进行技术格式化和作者校对之前会在网上发布。目的:Impella 微轴心室辅助装置需要葡萄糖清洗液与肝素或碳酸氢钠结合使用,以防止装置功能障碍和停机,但这些溶液中的葡萄糖会干扰正电子发射断层扫描 (PET),因此需要采用其他方法。摘要:我们介绍了在 2 例使用 Impella 5.5 心室辅助装置的患者中短期使用替代清洗液进行 PET 扫描以排除感染和恶性肿瘤的情况。由于氯化钠溶液可能会导致电机腐蚀,因此即使短时间内也不能与 Impella 心室辅助装置一起使用。因此,我们选择了无菌水基碳酸氢钠清洗液,并在 PET 扫描前和扫描过程中加入了短暂的无葡萄糖期。使用这种替代溶液成功进行了成像,在整个过程中对Impella性能水平和冲洗参数进行了监测,结果表明对泵的功能没有不良影响:结论:我们的无菌水基冲洗溶液加上短期限制使用葡萄糖是佩拉心室辅助装置患者 PET 成像的实用选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.90
自引率
18.50%
发文量
341
审稿时长
3-8 weeks
期刊介绍: The American Journal of Health-System Pharmacy (AJHP) is the official publication of the American Society of Health-System Pharmacists (ASHP). It publishes peer-reviewed scientific papers on contemporary drug therapy and pharmacy practice innovations in hospitals and health systems. With a circulation of more than 43,000, AJHP is the most widely recognized and respected clinical pharmacy journal in the world.
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