[Oral manifestation of a mantle cell lymphoma - a swelling in the buccal mucosa as the initial manifestation of mantle cell lymphoma: a case report].

Abstract

Lymphomas are malignant neoplasms of mature and immature B-cells, T-cells or NK-cells at various stages of differentiation. They predominantly occur in lymphoid tissues, manifestations in the oral cavity are rare: 3.5% of all oral malignancies are lymphomas. They often present an indolent course without systemic symptoms. Therefore, an early diagnosis by the dentist is important. We present a case of a mantle cell lymphoma in the oral cavity of an 80-year-old woman as a painless swelling of the buccal mucosa which represents the first sign of the disease. The oral biopsy, histologic and immunohistochemical diagnosis, further examinations and oncologic treatments are shown. Important clinical differential diagnoses are discussed.