Coronary artery thromboembolism as a cause of myocardial infarction with non-obstructive coronary arteries (MINOCA)

IF 2.7 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Hellenic Journal of Cardiology Pub Date : 2024-09-01 DOI:10.1016/j.hjc.2024.05.001

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Abstract

Acute myocardial infarction (AMI) usually represents the clinical manifestation of atherothrombotic coronary artery disease (CAD) resulting from atherosclerotic plaque rupture. However, there are cases in which coronary angiography or coronary computed tomography angiography reveals patients with acute coronary syndrome with non-obstructive CAD. This clinical entity is defined as myocardial infarction with non-obstructive coronary arteries (MINOCA) and often considered as a clinical dynamic working diagnosis that needs further investigations for the establishment of a final etiologic diagnosis. The main causes of a MINOCA working diagnosis include atherosclerotic, non-atherosclerotic (vessel-related and non–vessel-related), and thromboembolic causes This literature review aimed to investigate the major thromboembolic causes in patients presenting with MINOCA regarding their etiology and pathophysiologic mechanisms, as well as diagnostic and treatment methods.

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冠状动脉血栓栓塞是冠状动脉非阻塞性心肌梗死（MINOCA）的病因之一。

急性心肌梗死（AMI）通常是动脉粥样硬化斑块破裂导致的粥样血栓性冠状动脉疾病（CAD）的临床表现。然而，在某些情况下，冠状动脉造影术或冠状动脉计算机断层扫描血管造影术会发现急性冠状动脉综合征患者伴有非阻塞性 CAD。这种临床实体被定义为冠状动脉非阻塞性心肌梗死（MINOCA），通常被认为是一种临床动态工作诊断，需要进一步检查才能确定最终的病因诊断。导致 MINOCA 工作诊断的主要原因包括动脉粥样硬化、非动脉粥样硬化（血管相关和非血管相关）和血栓栓塞原因。本文献综述旨在从病因学、病理生理学机制以及诊断和治疗方法等方面研究 MINOCA 患者的主要血栓栓塞原因。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Hellenic Journal of Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

4.90

自引率

7.30%

发文量

审稿时长

56 days

期刊介绍： The Hellenic Journal of Cardiology (International Edition, ISSN 1109-9666) is the official journal of the Hellenic Society of Cardiology and aims to publish high-quality articles on all aspects of cardiovascular medicine. A primary goal is to publish in each issue a number of original articles related to clinical and basic research. Many of these will be accompanied by invited editorial comments. Hot topics, such as molecular cardiology, and innovative cardiac imaging and electrophysiological mapping techniques, will appear frequently in the journal in the form of invited expert articles or special reports. The Editorial Committee also attaches great importance to subjects related to continuing medical education, the implementation of guidelines and cost effectiveness in cardiology.