Lethal carbon monoxide generated from small internal combustion engines.

IF 2.3 3区 医学 Q3 CHEMISTRY, ANALYTICAL Journal of analytical toxicology Pub Date : 2024-10-28 DOI:10.1093/jat/bkae049
Brian E Hyson, Brittany M Friedman, Brianna Spear, Sandra C Bishop-Freeman
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Abstract

Fuel-burning small engines have the potential to emit dangerous and potentially lethal concentrations of carbon monoxide when used in poorly ventilated environments. The North Carolina Office of the Chief Medical Examiner investigated seven cases from 2013 to 2020 involving lethal carbon monoxide from small internal combustion engines. Evaluation of percent carboxyhemoglobin saturation was determined in these case studies as ratios of carboxyhemoglobin to reduced hemoglobin, using HP 8453 and Agilent 8454 UV-Visible Spectrophotometers (Agilent Technologies, Santa Clara, CA, USA). Sources of carbon monoxide included a pressure washer, a propane-powered forklift, an inboard engine boat, a motorcycle, propane and kerosene heaters, and home-use generators. It was demonstrated during a death investigation that the Dräger X-am 2000 electrochemical gas monitor often used by first responders, falsely reacted to acetylene gas, initially misleading investigators to the source of the carbon monoxide. Educating first responders about not only the hazards of these unexpected carbon monoxide sources, but the limitations of their equipment, is a valuable goal of disseminating complete medical examiner case information. The details of these cases will educate first responders, the forensic science community, and public health leaders on potential small engine sources of carbon monoxide in death investigations, responder safety, and the limitations of portable air quality monitoring equipment during death investigation.

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小型内燃机产生的致命一氧化碳。
在通风不良的环境中使用燃烧燃料的小型发动机时,有可能释放出危险且可能致命的高浓度一氧化碳。北卡罗来纳州首席法医办公室在 2013-2020 年间调查了七起涉及小型内燃机产生致命一氧化碳的案件。在这些案例研究中,使用 HP 8453 和 Agilent 8454 紫外-可见分光光度计(安捷伦科技公司,加利福尼亚州圣克拉拉)以碳氧血红蛋白与还原血红蛋白的比率来确定碳氧血红蛋白饱和度百分比的评估。一氧化碳的来源包括高压清洗机、丙烷动力叉车、内燃机船、摩托车、丙烷和煤油加热器以及家用发电机。在一次死亡调查中发现,急救人员经常使用的 Dräger X-am 2000 电化学气体监测仪对乙炔气体产生了错误的反应,最初误导了调查人员对一氧化碳来源的判断。教育急救人员不仅要了解这些意外一氧化碳来源的危害,还要了解其设备的局限性,这是传播完整法医案例信息的一个重要目标。这些案例的细节将使急救人员、法医科学界和公共卫生领导者了解死亡调查中一氧化碳的潜在小型发动机来源、急救人员的安全以及死亡调查过程中便携式空气质量监测设备的局限性。
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来源期刊
CiteScore
5.10
自引率
20.00%
发文量
92
审稿时长
6-12 weeks
期刊介绍: The Journal of Analytical Toxicology (JAT) is an international toxicology journal devoted to the timely dissemination of scientific communications concerning potentially toxic substances and drug identification, isolation, and quantitation. Since its inception in 1977, the Journal of Analytical Toxicology has striven to present state-of-the-art techniques used in toxicology labs. The peer-review process provided by the distinguished members of the Editorial Advisory Board ensures the high-quality and integrity of articles published in the Journal of Analytical Toxicology. Timely presentation of the latest toxicology developments is ensured through Technical Notes, Case Reports, and Letters to the Editor.
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