Surgical Resection and Immediate Reconstruction with a Bilayer Wound Collagen Matrix of a Rare Oral Angiosarcoma: A Case Report

Diseases Pub Date : 2024-06-03 DOI:10.3390/diseases12060117
Enzo Iacomino, Chiara Fratini, Laura Sollima, Alberto Eibenstein, Christian Barbato, M. de Vincentiis, Antonio Minni, Federica Zoccali
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Abstract

Angiosarcomas are malignant vascular tumors that commonly occur on the skin of the head and neck, breast, or scalp. Oral angiosarcoma is a rare tumor (0.0077% of all cancers in Europe), and regarding this atypical localization, no formal treatment trials have been conducted yet. We present a case of a 58-year-old female patient with a diagnosis of oral angiosarcoma. After tumor excision was performed by transoral surgical approach, immediate reconstruction of the intraoral surgical defects was made using Integra® bilayer wound collagen matrix. A skin regeneration technique has previously been reported to provide good healing for defects of buccal resection, preventing postoperative cicatricial fibrosis.
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罕见口腔血管肉瘤的手术切除和双层伤口胶原基质的即时重建:病例报告
血管肉瘤是一种恶性血管肿瘤,通常发生在头颈部、乳房或头皮的皮肤上。口腔血管肉瘤是一种罕见的肿瘤(占欧洲所有癌症的 0.0077%),对于这种不典型的定位,尚未进行过正式的治疗试验。我们报告了一例被诊断为口腔血管肉瘤的 58 岁女性患者的病例。经口手术切除肿瘤后,立即使用 Integra® 双层伤口胶原基质重建口腔内手术缺损。以前曾有报道称,皮肤再生技术可使口腔切除术后的缺损愈合良好,防止术后卡他性纤维化。
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