Alessandro Marchese, Gaia L'Abbate, Francesco Bandello, Elisabetta Miserocchi
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引用次数: 0
Abstract
Introduction: Chronic retinal necrosis encompasses severe occlusive retinal vasculitis, granular retinitis, and vitritis. This phenotype has been observed in patients with limited immune dysfunction, cytomegalovirus (CMV) uveitis, and negative serology for human immunodeficiency virus (HIV).
Methods: Case series.
Results: We present two cases: an 85-year-old female and a 76-year-old male, both displaying unusual occlusive panretinal vasculopathy associated with long-standing necrotizing retinitis and vitritis. Anterior chamber taps with real-time polymerase chain reaction (PCR) were negative for herpesviruses and positive for Toxoplasma gondii in both cases. These findings are consistent with chronic retinal necrosis associated with toxoplasma gondii.
Conclusions: In elderly patients or those with limited immune dysfunction who present with chronic retinal necrosis, Toxoplasma gondii should be considered in the differential diagnosis.
期刊介绍：
Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.
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