Extracranial metastasis from a frontal embryonal tumor to the parotid: Cytomorphologic features of a rare occurrence

IF 1 4区 医学 Q4 MEDICAL LABORATORY TECHNOLOGY Diagnostic Cytopathology Pub Date : 2024-06-15 DOI:10.1002/dc.25370
Anjali Gupta MD, Parikshaa Gupta MD, DNB, MIAC, Debajyoti Chatterjee MD, DM, Nalini Gupta MD, DNB, MIAC, Vikas Bhatia MD, DM
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Abstract

Embryonal tumors of the central nervous system (CNS) are rare and aggressive malignancies accounting for less than 1% of all central nervous system tumors. The occurrence of metastasis to extracranial sites, especially the parotid region, is highly uncommon. We present a rare case of metastatic frontal embryonal tumor (ET) in the parotid region. A 9-year-old boy presented with a progressively enlarging left parotid mass. Past history revealed that he was a known case of a frontal lobe embryonal tumor. Fine-needle aspiration cytology (FNAC) combined with immunocytochemistry from the parotid revealed a metastatic embryonal tumor. This case report highlights the importance of considering metastatic tumors in evaluating parotid masses, even in pediatric patients, and emphasizes the diagnostic potential of FNAC in diagnosing such rare and unusual tumors for prompt and appropriate patient management.

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额胚胎性肿瘤向腮腺的颅外转移:罕见病例的细胞形态学特征。
中枢神经系统(CNS)胚胎性肿瘤是一种罕见的侵袭性恶性肿瘤,占所有中枢神经系统肿瘤的 1%以下。向颅外部位,尤其是腮腺部位转移的情况非常罕见。我们报告了一例罕见的腮腺转移性额叶胚胎瘤(ET)病例。一名 9 岁男孩因左侧腮腺肿块逐渐增大而就诊。既往史显示,他曾患有额叶胚胎性肿瘤。腮腺细针穿刺细胞学(FNAC)结合免疫细胞化学发现了转移性胚胎性肿瘤。本病例报告强调了在评估腮腺肿块时考虑转移性肿瘤的重要性,即使在儿童患者中也是如此,并强调了 FNAC 在诊断此类罕见和不寻常肿瘤方面的诊断潜力,以便对患者进行及时和适当的治疗。
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来源期刊
Diagnostic Cytopathology
Diagnostic Cytopathology 医学-病理学
CiteScore
2.60
自引率
7.70%
发文量
163
审稿时长
3-6 weeks
期刊介绍: Diagnostic Cytopathology is intended to provide a forum for the exchange of information in the field of cytopathology, with special emphasis on the practical, clinical aspects of the discipline. The editors invite original scientific articles, as well as special review articles, feature articles, and letters to the editor, from laboratory professionals engaged in the practice of cytopathology. Manuscripts are accepted for publication on the basis of scientific merit, practical significance, and suitability for publication in a journal dedicated to this discipline. Original articles can be considered only with the understanding that they have never been published before and that they have not been submitted for simultaneous review to another publication.
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