A Case Report of an Adolescent Girl with Schizencephaly and Psychosis: Causal or Co-incidental?

Vishnupriya Veeraraghavan
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Abstract

Schizencephaly is an uncommon congenital malformation of the central nervous system. It affects the development of the cerebral cortex. It is characterized by a gray matter–lined cleft filled with cerebrospinal fluid that extends from the pial surface to the ventricle. Types are open and closed lip. Etiology can be due to localized ischemia in periventricular germinal matrix, an extreme variant of cortical dysplasia, and autosomal recessive gene involvement. Age of detection ranges from 8 months to 30 years. Scientific literature regarding the association between schizencephaly and psychosis is scarce. Here, we present the first adolescent case in the literature of a 16-year-old female child with schizencephaly and psychosis.
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一名患有精神分裂症和精神病的青春期女孩的病例报告:因果还是巧合?
精神分裂症是一种不常见的先天性中枢神经系统畸形。它影响大脑皮层的发育。其特征是灰质内衬的裂隙充满脑脊液,从皮质表面延伸到脑室。分为开唇型和闭唇型。病因可能是脑室周围生发基质局部缺血、皮质发育不良的极端变异以及常染色体隐性基因参与。发病年龄从 8 个月到 30 岁不等。有关精神分裂症与精神病之间关系的科学文献很少。在此,我们介绍了文献中第一例患有分裂体畸形和精神病的 16 岁女性青少年病例。
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CiteScore
0.70
自引率
16.70%
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0
期刊介绍: Journal of Indian Association for Child and Adolescent Mental Health (JIACAM) is a peer reviewed online journal. Uniform Requirements for Manuscripts Submitted to Biomedical Journals (http://www.icmje.org) will be followed. JIACAM accepts original articles, review articles, case reports, conference announcements, summary of trials, letters to the editor and conference reports.
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