Vitamin D Status and Longitudinal Changes in Body Composition in Patients with Chronic Obstructive Pulmonary Disease – A Prospective Observational Study

Maria Minter, Jenny van Odijk, Hanna Augustin, Felipe Machado, Frits Franssen, M. Spruit, L. Vanfleteren
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Abstract

Background: Alterations in body weight and composition are common in patients with chronic obstructive pulmonary disease (COPD) and are independent predictors for morbidity and mortality. Low vitamin D status is also more prevalent in patients with COPD compared to controls and has been related to lower lung function, muscle atrophy and impaired musculoskeletal function. This study aimed to evaluate the association between vitamin D levels and status with body composition (BC)
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维生素 D 状态与慢性阻塞性肺病患者身体成分的纵向变化--一项前瞻性观察研究
背景:慢性阻塞性肺病(COPD)患者的体重和组成发生变化是常见现象,也是发病率和死亡率的独立预测因素。与对照组相比,低维生素 D 状态在慢性阻塞性肺病患者中也更为普遍,并且与肺功能降低、肌肉萎缩和肌肉骨骼功能受损有关。本研究旨在评估维生素 D 水平和状态与身体成分(BC)之间的关系。
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