Cross-feeding of bifidobacteria promotes intestinal homeostasis: a lifelong perspective on the host health.

IF 7.8 1区生物学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY npj Biofilms and Microbiomes Pub Date : 2024-06-19 DOI:10.1038/s41522-024-00524-6

Meifang Xiao, Chuan Zhang, Hui Duan, Arjan Narbad, Jianxin Zhao, Wei Chen, Qixiao Zhai, Leilei Yu, Fengwei Tian

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Abstract

Throughout the life span of a host, bifidobacteria have shown superior colonization and glycan abilities. Complex glycans, such as human milk oligosaccharides and plant glycans, that reach the colon are directly internalized by the transport system of bifidobacteria, cleaved into simple structures by extracellular glycosyl hydrolase, and transported to cells for fermentation. The glycan utilization of bifidobacteria introduces cross-feeding activities between bifidobacterial strains and other microbiota, which are influenced by host nutrition and regulate gut homeostasis. This review discusses bifidobacterial glycan utilization strategies, focusing on the cross-feeding involved in bifidobacteria and its potential health benefits. Furthermore, the impact of cross-feeding on the gut trophic niche of bifidobacteria and host health is also highlighted. This review provides novel insights into the interactions between microbe-microbe and host-microbe.

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双歧杆菌交叉喂养促进肠道平衡：从宿主健康的终生角度看问题。

在宿主的整个生命周期中，双歧杆菌都表现出卓越的定植和聚糖能力。到达结肠的复杂聚糖（如人乳低聚糖和植物聚糖）会被双歧杆菌的运输系统直接内化，被细胞外糖基水解酶裂解为简单结构，并被运输到细胞中进行发酵。双歧杆菌对糖的利用在双歧杆菌菌株和其他微生物群之间引入了交叉饲养活动，这些活动受宿主营养的影响，并调节肠道平衡。本综述讨论了双歧杆菌的糖利用策略，重点是双歧杆菌参与的交叉进食及其潜在的健康益处。此外，还强调了交叉供食对双歧杆菌肠道营养位和宿主健康的影响。这篇综述为微生物-微生物和宿主-微生物之间的相互作用提供了新的见解。

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来源期刊

npj Biofilms and Microbiomes Immunology and Microbiology-Microbiology

CiteScore

12.10

自引率

3.30%

发文量

审稿时长

9 weeks

期刊介绍： npj Biofilms and Microbiomes is a comprehensive platform that promotes research on biofilms and microbiomes across various scientific disciplines. The journal facilitates cross-disciplinary discussions to enhance our understanding of the biology, ecology, and communal functions of biofilms, populations, and communities. It also focuses on applications in the medical, environmental, and engineering domains. The scope of the journal encompasses all aspects of the field, ranging from cell-cell communication and single cell interactions to the microbiomes of humans, animals, plants, and natural and built environments. The journal also welcomes research on the virome, phageome, mycome, and fungome. It publishes both applied science and theoretical work. As an open access and interdisciplinary journal, its primary goal is to publish significant scientific advancements in microbial biofilms and microbiomes. The journal enables discussions that span multiple disciplines and contributes to our understanding of the social behavior of microbial biofilm populations and communities, and their impact on life, human health, and the environment.