Combination Strategies and Targeted Radionuclide Therapies

IF 4.6 2区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Seminars in nuclear medicine Pub Date : 2024-07-01 DOI:10.1053/j.semnuclmed.2024.05.011
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Abstract

Combination models utilising treatments from two or more therapeutic classes are well established in cancer care. In the new era of theranostic (theragnostic) medicine there is an ongoing need to identify and refine novel combination strategies to optimise multidisciplinary care for conditions commonly encountered in nuclear medicine such as neuroendocrine neoplasms (NEN), prostate cancer (PCa), and thyroid cancer, along with seeking advancements in molecular imaging and therapy techniques for other tumour streams. This concise review explores the background of theranostic monotherapy, established approaches to combination strategies in theranostics, and emerging targeted radionuclide therapies in use or under active investigation, with a focus on Australian-led studies.

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组合策略和靶向放射性核素疗法。
在癌症治疗中,利用两种或两种以上治疗方法的联合治疗模式已经非常成熟。在新的治疗(诊断)医学时代,人们不断需要确定和完善新的联合治疗策略,以优化核医学中常见疾病的多学科治疗,如神经内分泌肿瘤(NEN)、前列腺癌(PCa)和甲状腺癌,同时寻求其他肿瘤流的分子成像和治疗技术的进步。这篇简明综述探讨了治疗放射性核素单一疗法的背景、治疗放射性核素联合疗法的既定方法以及正在使用或积极研究的新兴放射性核素靶向疗法,重点关注澳大利亚主导的研究。
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来源期刊
Seminars in nuclear medicine
Seminars in nuclear medicine 医学-核医学
CiteScore
9.80
自引率
6.10%
发文量
86
审稿时长
14 days
期刊介绍: Seminars in Nuclear Medicine is the leading review journal in nuclear medicine. Each issue brings you expert reviews and commentary on a single topic as selected by the Editors. The journal contains extensive coverage of the field of nuclear medicine, including PET, SPECT, and other molecular imaging studies, and related imaging studies. Full-color illustrations are used throughout to highlight important findings. Seminars is included in PubMed/Medline, Thomson/ISI, and other major scientific indexes.
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