Evaluation of cutout factors with small and narrow fields using various dosimetry detectors in electron beam keloid radiotherapy.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 DOI:10.3233/XST-240059
Yu-Fang Lin, Chen-Hsi Hsieh, Hui-Ju Tien, Yi-Huan Lee, Yi-Chun Chen, Lu-Han Lai, Shih-Ming Hsu, Pei-Wei Shueng
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Abstract

Background: The inherent problems in the existence of electron equilibrium and steep dose fall-off pose difficulties for small- and narrow-field dosimetry.

Objective: To investigate the cutout factors for keloid electron radiotherapy using various dosimetry detectors for small and narrow fields.

Method: The measurements were performed in a solid water phantom with nine different cutout shapes. Five dosimetry detectors were used in the study: pinpoint 3D ionization chamber, Farmer chamber, semiflex chamber, Classic Markus parallel plate chamber, and EBT3 film.

Results: The results demonstrated good agreement between the semiflex and pinpoint chambers. Furthermore, there was no difference between the Farmer and pinpoint chambers for large cutouts. For the EBT3 film, half of the cases had differences greater than 1%, and the maximum discrepancy compared with the reference chamber was greater than 2% for the narrow field.

Conclusion: The parallel plate, semiflex chamber and EBT3 film are suitable dosimeters that are comparable with pinpoint 3D chambers in small and narrow electron fields. Notably, a semiflex chamber could be an alternative option to a pinpoint 3D chamber for cutout widths≥3 cm. It is very important to perform patient-specific cutout factor calibration with an appropriate dosimeter for keloid radiotherapy.

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在电子束瘢痕疙瘩放射治疗中使用各种剂量检测器评估小场和窄场的切出因子。
背景:电子平衡和剂量陡降的固有问题给小野和窄野剂量测定带来了困难:目的:使用各种剂量测定探测器研究小场和窄场瘢痕电子放射治疗的切口系数:方法:在具有九种不同切口形状的固体水模型中进行测量。研究中使用了五种剂量测定探测器:针尖三维电离室、法玛室、半柔性室、经典马库斯平行板室和 EBT3 胶片:结果表明,半柔性电离室和针尖电离室之间的一致性很好。此外,法默室和针尖室在大切口方面没有差异。就 EBT3 胶片而言,半数病例的差异大于 1%,在窄视野中,与参考室相比的最大差异大于 2%:结论:平行板、半柔性腔体和 EBT3 薄膜都是合适的剂量计,在小电子场和窄电子场中可与针尖三维腔体相媲美。值得注意的是,在切口宽度≥3 厘米时,半柔性腔体可作为针尖三维腔体的替代选择。在瘢痕疙瘩放疗中,使用合适的剂量计对患者的特定切口系数进行校准非常重要。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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