Low Calf Circumference is Associated with Prolonged Hospital Stay in Older Patients with Solid Tumors: A Secondary Analysis of a Cohort Study.

IF 2 4区医学 Q3 NUTRITION & DIETETICS Nutrition and Cancer-An International Journal Pub Date : 2024-01-01 Epub Date: 2024-06-23 DOI:10.1080/01635581.2024.2364390

Laura Machado Scott, Giovanna Potrick Stefani, Camilla Horn Soares, Mariana Scortegagna Crestani, Thais Steemburgo

{"title":"Low Calf Circumference is Associated with Prolonged Hospital Stay in Older Patients with Solid Tumors: A Secondary Analysis of a Cohort Study.","authors":"Laura Machado Scott, Giovanna Potrick Stefani, Camilla Horn Soares, Mariana Scortegagna Crestani, Thais Steemburgo","doi":"10.1080/01635581.2024.2364390","DOIUrl":null,"url":null,"abstract":"Background: Older patients with cancer present intense loss of muscle mass (MM). Calf circumference (CC) is a simple measurement that assesses MM. This study analyzed the accuracy and association between low CC and negative outcomes in older patients with solid tumors.Methods: A secondary analysis of a prospective cohort study of inpatients with cancer was conducted. Low CC was defined as CC ≤34 cm in males and ≤33 cm in females. The CC was adjusted for body mass index by reducing 3 or 7 cm for BMI (in kg/m2) of 25-29.9 and 30-39.9, respectively. Accuracy tests and regression analyses were performed to evaluate the criterion validity of low CC for predicting length of stay (LOS) and readmission.Results: A total of 248 inpatients were evaluated (69.7 [standard deviation (SD) 7.2]; 59.7% men). Among them, 31% had a low CC. A low CC (crude and adjusted for BMI) showed poor performance in predicting LOS and readmission. In the adjusted analysis, older patients with low CC had a 2.45-fold increased risk of LOS ≥ 4 days.Conclusion: Low CC did not perform well in predicting negative outcomes in older patients with solid tumors. However, low CC was positively associated with LOS.","PeriodicalId":54701,"journal":{"name":"Nutrition and Cancer-An International Journal","volume":" ","pages":"726-735"},"PeriodicalIF":2.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nutrition and Cancer-An International Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/01635581.2024.2364390","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/23 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Older patients with cancer present intense loss of muscle mass (MM). Calf circumference (CC) is a simple measurement that assesses MM. This study analyzed the accuracy and association between low CC and negative outcomes in older patients with solid tumors.

Methods: A secondary analysis of a prospective cohort study of inpatients with cancer was conducted. Low CC was defined as CC ≤34 cm in males and ≤33 cm in females. The CC was adjusted for body mass index by reducing 3 or 7 cm for BMI (in kg/m²) of 25-29.9 and 30-39.9, respectively. Accuracy tests and regression analyses were performed to evaluate the criterion validity of low CC for predicting length of stay (LOS) and readmission.

Results: A total of 248 inpatients were evaluated (69.7 [standard deviation (SD) 7.2]; 59.7% men). Among them, 31% had a low CC. A low CC (crude and adjusted for BMI) showed poor performance in predicting LOS and readmission. In the adjusted analysis, older patients with low CC had a 2.45-fold increased risk of LOS ≥ 4 days.

Conclusion: Low CC did not perform well in predicting negative outcomes in older patients with solid tumors. However, low CC was positively associated with LOS.

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

实体瘤老年患者的低小腿围与住院时间延长有关：一项队列研究的二次分析。

背景：老年癌症患者的肌肉质量（MM）严重下降。小腿围（CC）是评估肌肉质量的一种简单测量方法。本研究分析了低 CC 与老年实体瘤患者不良预后之间的准确性和关联性：方法：对癌症住院患者的前瞻性队列研究进行了二次分析。低 CC 的定义是男性 CC ≤34 厘米，女性 CC ≤33 厘米。CC根据体重指数进行调整，体重指数（以千克/平方米为单位）为25-29.9和30-39.9时，CC分别减少3或7厘米。为了评估低 CC 在预测住院时间（LOS）和再入院方面的标准有效性，进行了准确性测试和回归分析：共评估了 248 名住院患者（69.7 [标准差（SD）7.2]；59.7% 为男性）。其中，31%的患者有低 CC。低 CC（粗略和根据体重指数调整后）在预测 LOS 和再入院方面表现不佳。在调整后的分析中，低 CC 老年患者的 LOS ≥ 4 天的风险增加了 2.45 倍：低CC不能很好地预测老年实体瘤患者的不良预后。然而，低CC与LOS呈正相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Nutrition and Cancer-An International Journal 医学-营养学

CiteScore

5.80

自引率

3.40%

发文量

172

审稿时长

3 months

期刊介绍： This timely publication reports and reviews current findings on the effects of nutrition on the etiology, therapy, and prevention of cancer. Etiological issues include clinical and experimental research in nutrition, carcinogenesis, epidemiology, biochemistry, and molecular biology. Coverage of therapy focuses on research in clinical nutrition and oncology, dietetics, and bioengineering. Prevention approaches include public health recommendations, preventative medicine, behavior modification, education, functional foods, and agricultural and food production policies.