A Rare Co-existent Case of Splenic Microfilariasis and Pancreatic Solid Pseudopapillary Epithelial Neoplasm - A Double Jeopardy!

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL International Journal of Applied and Basic Medical Research Pub Date : 2024-04-01 Epub Date: 2024-05-24 DOI:10.4103/ijabmr.ijabmr_464_23
Sangeeta Kini, Rima N Kamat, Sneha Janjal, Heena M Desai
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Abstract

Filariasis is a major public health concern in tropical and subtropical countries like India with Wuchereria bancrofti accounting for 90% of lymphatic filariasis. Rarely observed are extra lymphatic manifestations caused by interaction of immune system with microfilaria and their diffusible products. Among various organs involved, splenic involvement is a rare extra lymphatic manifestation of filariasis and can masquerade clinicoradiologically as metastasis when associated with a known malignancy or as a primary malignancy like lymphoma. Hereby, we present an unusual case of coincidence of splenic filariasis with pancreatic solid pseudopapillary epithelial neoplasm in a 20-year-old woman associated with peripheral blood eosinophilia.

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脾脏微丝虫病和胰腺实性假乳头状上皮肿瘤并存的罕见病例--双重危险!
丝虫病是印度等热带和亚热带国家的主要公共卫生问题,其中90%的淋巴丝虫病是由班氏武契罗菲亚(Wuchereria bancrofti)引起的。由于免疫系统与微丝蚴及其扩散产物相互作用而引起的淋巴外表现很少见。在各种受累器官中,脾脏受累是丝虫病罕见的淋巴外表现,临床放射学上可表现为与已知恶性肿瘤相关的转移瘤或淋巴瘤等原发性恶性肿瘤。在此,我们介绍了一例不寻常的病例,患者为一名20岁女性,伴有外周血嗜酸性粒细胞增多,同时患有脾丝虫病和胰腺实性假乳头状上皮肿瘤。
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