Paper based analytical platforms: A matrix adaptable approach to drug testing

IF 4.1 Q1 CHEMISTRY, ANALYTICAL Talanta Open Pub Date : 2024-06-18 DOI:10.1016/j.talo.2024.100338
Naga Prashant Koppuravuri, Suvarna Yenduri, Rukaiya Nabi, Pooja M, Aishwarya N, Sanika M, Sinchana Prakash
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Abstract

Paper-based analytical devices (PADs) are becoming increasingly popular for drug analysis in various matrices. These affordable, portable platforms come with a range of benefits, such as their user-friendly design, straightforward operation, and minimal need for sample preparation. This study evaluates the potential applications of PADs in drug testing with a particular emphasis on the adaptability of PADs in terms of their ability to handle various types of samples during the testing process. In this study, the design, manufacturing, and performance of PADs for drug detection, as well as the influence that different biological samples have on the performance of PAD performance were investigated. PADs are discussed in this paper, with respect to their applications in forensic sample analysis, point-of-care testing and illicit drug testing. The study demonstrates the flexibility of PADs as platforms for drug testing in varied matrices. The authors highlight the fact that PADs are inexpensive, portable, user-friendly, and need minimum sample preparation, which makes them effective instruments in a variety of situations, including research, law enforcement, and healthcare. On the whole, this paper highlights the versatility of PADs, emphasizing their role as adaptable platforms for drug testing within different matrices. Scientists and professionals can utilize these cutting-edge devices to improve the efficiency and accessibility of drug analysis.

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基于纸张的分析平台:药物检测的矩阵适应性方法
纸质分析装置(PAD)在各种基质的药物分析中越来越受欢迎。这些经济实惠的便携式平台具有一系列优点,如设计方便用户、操作简单、样品制备的需求极低。本研究评估了 PAD 在药物检测中的潜在应用,特别强调了 PAD 在检测过程中处理各类样品的适应性。本研究调查了用于药物检测的 PAD 的设计、制造和性能,以及不同生物样本对 PAD 性能的影响。本文讨论了 PAD 在法医样本分析、护理点检测和非法药物检测中的应用。研究证明了 PAD 作为不同基质中药物检测平台的灵活性。作者强调,PAD 价格低廉、便于携带、使用方便,只需最少的样品制备,因此是研究、执法和医疗保健等各种情况下的有效仪器。总体而言,本文突出了 PAD 的多功能性,强调了其作为在不同基质中进行药物检测的适应性平台的作用。科学家和专业人员可以利用这些尖端设备来提高药物分析的效率和便利性。
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来源期刊
Talanta Open
Talanta Open Chemistry-Analytical Chemistry
CiteScore
5.20
自引率
0.00%
发文量
86
审稿时长
49 days
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