Sleep Disorders and Dementia Risk in Older Patients with Kidney Failure: A Retrospective Cohort Study.

IF 8.5 1区 医学 Q1 UROLOGY & NEPHROLOGY Clinical Journal of the American Society of Nephrology Pub Date : 2024-10-01 Epub Date: 2024-06-24 DOI:10.2215/CJN.0000000000000504
Jane J Long, Yusi Chen, Byoungjun Kim, Sunjae Bae, Yiting Li, Babak J Orandi, Nadia M Chu, Aarti Mathur, Dorry L Segev, Mara A McAdams-DeMarco
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肾衰竭老年患者的睡眠障碍与痴呆风险:一项回顾性队列研究
背景:患有睡眠障碍的社区老年人患痴呆症的风险较高。50%以上的肾衰竭老年患者有睡眠障碍,这可能是他们患痴呆症的高风险原因:在 216,158 名肾衰竭患者(年龄≥66 岁)中(美国肾脏数据系统;2008-2019 年),我们使用带有倾向得分加权的 Cox 比例危险模型估算了与睡眠障碍相关的痴呆风险(包括亚型)。结果:26.3%的患者被诊断出患有睡眠障碍;这些患者任何类型痴呆症的五年未调整累积发病率较高(36.2% 对 32.3%;PC结论:患有睡眠障碍的老年肾衰竭患者的痴呆症发病率较高:患有肾衰竭和睡眠障碍的老年患者患痴呆症的风险较高。睡眠是一个重要的可改变因素,应考虑采取有针对性的干预措施来降低肾衰竭患者患痴呆症的风险。对患有 OSA 的患者来说,PAP 治疗与降低痴呆症风险有关。
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来源期刊
CiteScore
12.20
自引率
3.10%
发文量
514
审稿时长
3-6 weeks
期刊介绍: The Clinical Journal of the American Society of Nephrology strives to establish itself as the foremost authority in communicating and influencing advances in clinical nephrology by (1) swiftly and effectively disseminating pivotal developments in clinical and translational research in nephrology, encompassing innovations in research methods and care delivery; (2) providing context for these advances in relation to future research directions and patient care; and (3) becoming a key voice on issues with potential implications for the clinical practice of nephrology, particularly within the United States. Original manuscript topics cover a range of areas, including Acid/Base and Electrolyte Disorders, Acute Kidney Injury and ICU Nephrology, Chronic Kidney Disease, Clinical Nephrology, Cystic Kidney Disease, Diabetes and the Kidney, Genetics, Geriatric and Palliative Nephrology, Glomerular and Tubulointerstitial Diseases, Hypertension, Maintenance Dialysis, Mineral Metabolism, Nephrolithiasis, and Transplantation.
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