Physochlainae Radix: A Review of Ethnobotany, Phytochemistry, Pharmacology, Q-marker Prediction, and Future Directions.

IF 2.9 4区医学 Q3 CHEMISTRY, MEDICINAL Current topics in medicinal chemistry Pub Date : 2024-01-01 DOI:10.2174/0115680266287982240517050139

Xin-Bo Zhang, Peiyuan Zhao, Yunlan Wang, Ying Zhang, Xuan Lei, Xiao Song

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Abstract

Background: Upon the release of the selection results of "Qin Medicine," numerous Chinese herbal medicines and proprietary Chinese medicines have regained attention. Physochlainae Radix (Huashanshen), a herbal medicine named after Mount Hua, the prominent peak in the Qinling Mountains, has garnered particular interest. Despite this, the impact of Physochlainae Radix and Qin medicines as a whole remains significantly overshadowed by the renown of Mount Hua.

Methods: Search on Using "Physochlainae Radix" as the keyword; searches were conducted across China National Knowledge Infrastructure (CNKI), Wanfang Data, WIP Database, PubMed, Web of Science, and the National Library of China databases.

Results: This study presents an overview of Physochlainae Radix by reviewing its history, chemical composition, preparation methods, planting and cultivation practices, concoctions, alkaloid detection, contraindications for use, resource recycling, and predicting quality markers.

Conclusion: To facilitate the further application and development of Physochlainae Radix, this study also addresses the challenges in the development of Qin medicines and proposes potential solutions.

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药用植物：民族植物学、植物化学、药理学、Q 标记预测和未来方向综述。

背景：秦医》遴选结果公布后，众多中药材和中成药重新受到关注。其中，以秦岭主峰华山命名的 "华山参 "尤为引人关注。尽管如此，"华山 "的名气仍然远远盖过了 "秦药 "和 "秦药 "的影响力：以 "川贝母 "为关键词，在中国国家知识基础设施（CNKI）、万方数据、WIP 数据库、PubMed、Web of Science 和中国国家图书馆数据库中进行检索：本研究通过回顾其历史、化学成分、制备方法、种植和栽培方法、炮制方法、生物碱检测、使用禁忌、资源回收利用和质量指标预测等内容，概述了苏合香属植物：结论：为了促进秦艽的进一步应用和发展，本研究还探讨了秦药发展过程中面临的挑战，并提出了潜在的解决方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current topics in medicinal chemistry 医学-医药化学

CiteScore

6.40

自引率

2.90%

发文量

186

审稿时长

3-8 weeks

期刊介绍： Current Topics in Medicinal Chemistry is a forum for the review of areas of keen and topical interest to medicinal chemists and others in the allied disciplines. Each issue is solely devoted to a specific topic, containing six to nine reviews, which provide the reader a comprehensive survey of that area. A Guest Editor who is an expert in the topic under review, will assemble each issue. The scope of Current Topics in Medicinal Chemistry will cover all areas of medicinal chemistry, including current developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, and structure-activity relationships. Medicinal chemistry is a rapidly maturing discipline. The study of how structure and function are related is absolutely essential to understanding the molecular basis of life. Current Topics in Medicinal Chemistry aims to contribute to the growth of scientific knowledge and insight, and facilitate the discovery and development of new therapeutic agents to treat debilitating human disorders. The journal is essential for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important advances.