[Numerical study of the effect of geometrical parameters of straight impellers on the flow and hemolysis performance of centrifugal blood pumps].

Dongmei Huang, Siheng Xiong, Yuan Xiao, Jinyang Wang, Guomin Cui
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Abstract

Red blood cells are destroyed when the shear stress in the blood pump exceeds a threshold, which in turn triggers hemolysis in the patient. The impeller design of centrifugal blood pumps significantly influences the hydraulic characteristics and hemolytic properties of these devices. Based on this premise, the present study employs a multiphase flow approach to numerically simulate centrifugal blood pumps, investigating the performance of pumps with varying numbers of blades and blade deflection angles. This analysis encompassed the examination of flow field characteristics, hydraulic performance, and hemolytic potential. Numerical results indicated that the concentration of red blood cells and elevated shear stresses primarily occurred at the impeller and volute tongue, which drastically increased the risk of hemolysis in these areas. It was found that increasing the number of blades within a certain range enhanced the hydraulic performance of the pump but also raised the potential for hemolysis. Moreover, augmenting the blade deflection angle could improve the hemolytic performance, particularly in pumps with a higher number of blades. The findings from this study can provide valuable insights for the structural improvement and performance enhancement of centrifugal blood pumps.

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[直叶轮几何参数对离心血泵流量和溶血性能影响的数值研究]。
当血泵中的剪切应力超过阈值时,红细胞就会被破坏,进而引发患者溶血。离心式血泵的叶轮设计会极大地影响这些设备的水力特性和溶血特性。基于这一前提,本研究采用多相流方法对离心式血泵进行数值模拟,研究叶片数量和叶片偏转角度不同的泵的性能。该分析包括对流场特征、水力性能和溶血潜能的研究。数值结果表明,红细胞聚集和剪应力升高主要发生在叶轮和涡舌处,这大大增加了这些区域发生溶血的风险。研究发现,在一定范围内增加叶片数量可提高泵的水力性能,但同时也增加了溶血的可能性。此外,增加叶片偏转角可以改善溶血性能,尤其是在叶片数量较多的泵中。这项研究的结果可为离心血泵的结构改进和性能提升提供有价值的启示。
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来源期刊
生物医学工程学杂志
生物医学工程学杂志 Medicine-Medicine (all)
CiteScore
0.80
自引率
0.00%
发文量
4868
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