Performance of a rapid recency assay for detection of early HIV infection

IF 4 3区 医学 Q2 VIROLOGY Journal of Clinical Virology Pub Date : 2024-06-22 DOI:10.1016/j.jcv.2024.105708
Clara Di Germanio , Xutao Deng , Eduard Grebe , Jeffrey A. Johnson , Silvina Masciotra , Michael P. Busch , Philip J. Norris
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Abstract

The Asanté HIV-1 Rapid Recency assay's ‘verification’ line detected HIV infection a median of 18 days later than a nucleic acid detection assay and performed similarly to 19 other existing rapid HIV antibody tests. Pending regulatory approval, the assay could be an option with other rapid tests in national HIV-1 testing algorithms, which would allow collection of HIV recency data as part of a national screening program without requiring additional testing.

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用于检测早期艾滋病病毒感染的快速复发测定的性能。
Asanté HIV-1 快速复发检测的 "验证 "线检测出艾滋病毒感染的时间比核酸检测中位晚18天,与其他19种现有的快速艾滋病毒抗体检测结果相似。在获得监管部门批准后,该检测法可与其他快速检测法一起作为国家 HIV-1 检测算法的一个选项,这样就可以收集 HIV 复发率数据,作为国家筛查计划的一部分,而不需要额外的检测。
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来源期刊
Journal of Clinical Virology
Journal of Clinical Virology 医学-病毒学
CiteScore
22.70
自引率
1.10%
发文量
149
审稿时长
24 days
期刊介绍: The Journal of Clinical Virology, an esteemed international publication, serves as the official journal for both the Pan American Society for Clinical Virology and The European Society for Clinical Virology. Dedicated to advancing the understanding of human virology in clinical settings, the Journal of Clinical Virology focuses on disseminating research papers and reviews pertaining to the clinical aspects of virology. Its scope encompasses articles discussing diagnostic methodologies and virus-induced clinical conditions, with an emphasis on practicality and relevance to clinical practice. The journal publishes on topics that include: • new diagnostic technologies • nucleic acid amplification and serologic testing • targeted and metagenomic next-generation sequencing • emerging pandemic viral threats • respiratory viruses • transplant viruses • chronic viral infections • cancer-associated viruses • gastrointestinal viruses • central nervous system viruses • one health (excludes animal health)
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