Cover Image, Volume 62, Issue 13

Abstract

The cover image is based on the Research Article Synthesis and chiroptical properties of β-1,2-linked glycopolymers prepared by click polymerization by Misaki Suzuki et al., https://doi.org/10.1002/pol.20230746

In the cover image, Yasuhito Koyama and coworkers show the design, synthesis, and folding behaviors of β-1,2-linked glycopolymers as a bioconjugate-based foldamer. The glycopolymers are synthesized via the click polymerization of alkyne-containing β-glycosyl azides. The galactose-based polymer adopts a helically folded structure in ClCH₂CH₂Cl or THF. It is indicated that the glucose-based polymer can possibly form the helical folded structure in ClCH₂CH₂Cl at a low temperature region and adopt a random coil structure at 50 °C. In THF, the glucose-based polymer does not fold the conformation at all in the observed temperature region.