The Structural Biology of Catalase Evolution.

Q1 Biochemistry, Genetics and Molecular Biology Sub-cellular biochemistry Pub Date : 2024-01-01 DOI:10.1007/978-3-031-58843-3_3
María Belén López, María Belén Oterino, Javier M González
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Abstract

Catalases are essential enzymes for removal of hydrogen peroxide, enabling aerobic and anaerobic metabolism in an oxygenated atmosphere. Monofunctional heme catalases, catalase-peroxidases, and manganese catalases, evolved independently more than two billion years ago, constituting a classic example of convergent evolution. Herein, the diversity of catalase sequences is analyzed through sequence similarity networks, providing the context for sequence distribution of major catalase families, and showing that many divergent catalase families remain to be experimentally studied.

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过氧化氢酶进化的结构生物学。
过氧化氢酶是清除过氧化氢的重要酶类,可在含氧环境中进行有氧和无氧新陈代谢。单功能血红素过氧化氢酶、过氧化氢酶和锰过氧化氢酶在 20 多亿年前独立进化,是趋同进化的典型例子。本文通过序列相似性网络分析了过氧化氢酶序列的多样性,为主要过氧化氢酶家族的序列分布提供了背景,并表明许多不同的过氧化氢酶家族仍有待实验研究。
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来源期刊
Sub-cellular biochemistry
Sub-cellular biochemistry Biochemistry, Genetics and Molecular Biology-Biochemistry
CiteScore
5.90
自引率
0.00%
发文量
33
期刊介绍: The book series SUBCELLULAR BIOCHEMISTRY is a renowned and well recognized forum for disseminating advances of emerging topics in Cell Biology and related subjects. All volumes are edited by established scientists and the individual chapters are written by experts on the relevant topic. The individual chapters of each volume are fully citable and indexed in Medline/Pubmed to ensure maximum visibility of the work.
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