[Cancer genomic panels for lymphoid malignancies].

Daisuke Ennishi
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Abstract

Cancer precision medicine (genome-based individualized treatment for cancer patients) has already been introduced for solid tumors, and involves identifying driver genes in the development and progression of tumors and suggesting optimal treatments targeting those genes. So far, many patients have received this style of treatment. Meanwhile, preparations for cancer genomic medicine based on cancer gene panel testing are also underway for hematopoietic tumors. In this article, I would like to share fundamental information about the main genetic mutations in malignant lymphomas and their clinical significance, and discuss how this information should be utilized in cancer genomic medicine in the future.

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[淋巴恶性肿瘤的癌症基因组面板]。
癌症精准医疗(基于基因组的癌症患者个体化治疗)已被引入实体瘤领域,包括识别肿瘤发生和发展过程中的驱动基因,并提出针对这些基因的最佳治疗方案。迄今为止,已有许多患者接受了这种治疗方式。同时,针对造血肿瘤的基于癌症基因面板检测的癌症基因组医疗也在筹备之中。在这篇文章中,我想与大家分享恶性淋巴瘤主要基因突变的基本信息及其临床意义,并讨论未来癌症基因组医学应如何利用这些信息。
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