Static and temporal dynamic alterations of regional homogeneity in chronic insomnia: a resting-state fMRI study

IF 1 4区 医学 Q4 CLINICAL NEUROLOGY Sleep and Biological Rhythms Pub Date : 2024-07-02 DOI:10.1007/s41105-024-00541-0
Xiaoxin Chen, Wenzheng Zhang, Maoyang Wang, Jun Li
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Abstract

To explore brain function alterations in chronic insomnia (CI). 65 CI patients and 48 healthy controls were included to analyze abnormal alterations in brain spontaneous activity using static regional homogeneity (sReHo) and dynamic regional homogeneity (dReHo) methods. CI patients focused on decreased sReHo in bilateral lingual gyrus, bilateral middle occipital gyrus, bilateral inferior occipital gyrus and right superior occipital gyrus; decreased dReHo in bilateral superior occipital gyrus, bilateral cortical area around the talus fissure, and right middle occipital gyrus. CI patients exhibit abnormal activity in multiple brain regions, which can reflect the sleep quality index.

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慢性失眠症区域同质性的静态和时态动态变化:静息态 fMRI 研究
探讨慢性失眠症(CI)患者大脑功能的改变。研究对象包括65名慢性失眠症患者和48名健康对照者,采用静态区域同质性(sReHo)和动态区域同质性(dReHo)方法分析大脑自发活动的异常改变。CI 患者的 sReHo 主要集中在双侧舌回、双侧枕中回、双侧枕下回和右侧枕上回;dReHo 主要集中在双侧枕上回、距骨裂周围的双侧皮质区和右侧枕中回。CI 患者在多个脑区表现出异常活动,这可以反映睡眠质量指数。
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来源期刊
Sleep and Biological Rhythms
Sleep and Biological Rhythms 医学-临床神经学
CiteScore
2.20
自引率
9.10%
发文量
71
审稿时长
>12 weeks
期刊介绍: Sleep and Biological Rhythms is a quarterly peer-reviewed publication dealing with medical treatments relating to sleep. The journal publishies original articles, short papers, commentaries and the occasional reviews. In scope the journal covers mechanisms of sleep and wakefullness from the ranging perspectives of basic science, medicine, dentistry, pharmacology, psychology, engineering, public health and related branches of the social sciences
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