195 A better way to fill exposure data gaps

IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Annals Of Work Exposures and Health Pub Date : 2024-06-27 DOI:10.1093/annweh/wxae035.076
Mi (Jennifer) Shin, Hua Qian, Jee-Eun Lee, Luis Sentis, Silvia Maberti
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Abstract

Exposure assessment is a core component of regulatory quantitative risk assessment and plays a central role in risk management. Ideally, personal exposure measurements are collected using techniques that record an individual’s direct exposures. Though this type of data is preferred, it is often lacking. In this study, we tested whether a robot could be programmed to simulate human use of spray products and then used in place of human subjects for generating air concentration data. A robot was programmed to simulate human use of a fabric crafts protector (FCP) and a glass cleaning (GC) product. While the robot used these products, air sampling data was collected to estimate VOC concentrations. The sampling data was summarized and then compared to air concentration data found in the literature while humans used similar products. In this study we successfully programmed a robot to mimic human use of two spray products. Average VOC concentrations were 1.57 ppm for FCP spraying and 0.17 ppm for GC spraying and wiping. Air sampling data were found to be within the range of data reported in the literature. This study demonstrates the ability to use robots to simulate human exposures. It offers a systematic, efficient method for generating exposure data where gaps exist. This data can be used to validate or enhance models and improve health and safety risk assessments used for public health protection.
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195 填补暴露数据缺口的更好方法
暴露评估是监管定量风险评估的核心组成部分,在风险管理中发挥着核心作用。理想情况下,个人暴露测量数据是通过记录个人直接暴露的技术收集的。虽然这类数据是首选,但往往缺乏。在这项研究中,我们测试了是否可以对机器人进行编程,以模拟人类使用喷雾产品的情况,然后用机器人代替人类来生成空气浓度数据。我们对机器人进行了编程,以模拟人类使用织物工艺保护剂 (FCP) 和玻璃清洁剂 (GC) 产品。在机器人使用这些产品时,收集空气采样数据以估算挥发性有机化合物的浓度。我们对采样数据进行了汇总,然后与文献中人类使用类似产品时的空气浓度数据进行了比较。在这项研究中,我们成功地对机器人进行了编程,以模仿人类使用两种喷雾产品。喷洒 FCP 时的平均挥发性有机化合物浓度为 1.57 ppm,喷洒和擦拭 GC 时的平均挥发性有机化合物浓度为 0.17 ppm。空气采样数据与文献报道的数据相符。这项研究证明了使用机器人模拟人类接触的能力。它提供了一种系统、高效的方法来生成存在差距的暴露数据。这些数据可用于验证或增强模型,并改进用于公共健康保护的健康和安全风险评估。
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来源期刊
Annals Of Work Exposures and Health
Annals Of Work Exposures and Health Medicine-Public Health, Environmental and Occupational Health
CiteScore
4.60
自引率
19.20%
发文量
79
期刊介绍: About the Journal Annals of Work Exposures and Health is dedicated to presenting advances in exposure science supporting the recognition, quantification, and control of exposures at work, and epidemiological studies on their effects on human health and well-being. A key question we apply to submission is, "Is this paper going to help readers better understand, quantify, and control conditions at work that adversely or positively affect health and well-being?" We are interested in high quality scientific research addressing: the quantification of work exposures, including chemical, biological, physical, biomechanical, and psychosocial, and the elements of work organization giving rise to such exposures; the relationship between these exposures and the acute and chronic health consequences for those exposed and their families and communities; populations at special risk of work-related exposures including women, under-represented minorities, immigrants, and other vulnerable groups such as temporary, contingent and informal sector workers; the effectiveness of interventions addressing exposure and risk including production technologies, work process engineering, and personal protective systems; policies and management approaches to reduce risk and improve health and well-being among workers, their families or communities; methodologies and mechanisms that underlie the quantification and/or control of exposure and risk. There is heavy pressure on space in the journal, and the above interests mean that we do not usually publish papers that simply report local conditions without generalizable results. We are also unlikely to publish reports on human health and well-being without information on the work exposure characteristics giving rise to the effects. We particularly welcome contributions from scientists based in, or addressing conditions in, developing economies that fall within the above scope.
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