Spatially heterogeneous dynamics of droplets formed by arginine-rich dipeptides and poly-A RNA during liquid-liquid phase separation

IF 0.7 4区 化学 Q4 CHEMISTRY, MULTIDISCIPLINARY Molecular Crystals and Liquid Crystals Pub Date : 2024-05-29 DOI:10.1080/15421406.2024.2353937
Ya Tian, Qiang Zhang, Kenji Hirai, Han Wen, Guilin Feng, Jiangtao Li, Farsai Taemaitree, Tomoko Inose, Kohsuke Kanekura, Hiroshi Uji-i
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Abstract

Arginine-rich dipeptides (proline-arginine (PR)) are highly toxic products encoded by aberrant repeat expansion in the C9ORF72 gene, which is the most common cause of familial amyotrophic lateral s...
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富精氨酸二肽和聚 A 型 RNA 在液-液相分离过程中形成的液滴的空间异构动力学
富含精氨酸的二肽(脯氨酸-精氨酸(PR))是 C9ORF72 基因异常重复扩增编码的剧毒产物,而 C9ORF72 基因是家族性肌萎缩侧索硬化症最常见的病因。
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来源期刊
CiteScore
1.20
自引率
14.30%
发文量
248
审稿时长
2 months
期刊介绍: Established in 1966, Molecular Crystals and Liquid Crystals is a world-leading journal publishing original research papers in both an experimental and theoretical nature in three areas of specialization: liquid crystals, molecular crystals, and low-dimensional solids. These cover, but are not limited to: Liquid Crystals: -Electro- and magneto-optical phenomena; thermodynamics; phase transitions; structure; NMR and orientation-controlled spectroscopy; theory. Molecular Crystals: -Spectroscopy; energy and charge transfer; solid state reactions; photo and radiation effects Low-dimensional Solids: -Structure, electronic, magnetic, and optical properties; transport mechanisms The journal publishes research papers, review papers, and book reviews. In all three areas, experimental manuscripts describing both preparation and properties will be considered. Papers that describe determination of crystal structure alone are not encouraged unless some solid state forces (hydrogen bonding, charge transfer, etc.) are playing a significant role and/or some solid state properties of the materials are measured.
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