Extensive folliculitis and abscesses with a sporotrichoid distribution in a parenteral drug user.

IF 1.9 4区 医学 Q3 INFECTIOUS DISEASES Journal of Infection and Chemotherapy Pub Date : 2024-07-03 DOI:10.1016/j.jiac.2024.06.022
Victoria Lobo-Antuña, Andrés Grau-Echevarría, Marta Lobo-Antuña, Sofia Russo-Botero, Laura Mascarell-Escrivá, Violeta Zaragoza-Ninet, Josep Marí-Alexandre, Esther Jaén-Ferrer, Jose Ignacio Mateo-González
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Abstract

We present the case of a 53-year-old Caucasian man with a history of intravenous drug use who presented with fever and multiple pustules predominantly affecting hairy areas of the body, with no clinical improvement despite previous antibiotic treatment. Culture of the pustules confirmed Candida albicans infection and histological examination of skin biopsies revealed suppurative granulomas compatible with candidomycetic folliculitis. The patient was successfully treated with systemic antifungals and discharged with resolution of symptoms. Candidomycetic folliculitis is a condition typically associated with brown heroin consumption due to the use of acidic solvent that promotes Candida growth. Clinical manifestations include fever followed by skin lesions, with possible systemic involvement if untreated. Extensive folliculitis with associated fever in an IVDU should raise suspicion of this pathology since early diagnosis and appropriate treatment are crucial to prevent complications.

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一名肠外用药者身上出现分布有孢子丝菌的广泛毛囊炎和脓肿。
本病例涉及一名 53 岁的白种男子,他有静脉注射毒品史,曾出现发热和多发性脓疱,主要累及身体多毛部位,尽管之前接受过抗生素治疗,但临床症状没有改善。脓疱培养证实感染了白色念珠菌,皮肤活检组织学检查显示化脓性肉芽肿与念珠菌性毛囊炎相符。患者接受了全身抗真菌治疗,症状缓解后出院。念珠菌性毛囊炎通常与吸食棕色海洛因有关,因为使用酸性溶剂会促进念珠菌生长。临床表现包括发热,随后出现皮损,如不及时治疗可能会累及全身。在 IVDU 中出现大面积毛囊炎并伴有发热时,应怀疑这种病症,因为早期诊断和适当治疗对预防并发症至关重要。
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来源期刊
Journal of Infection and Chemotherapy
Journal of Infection and Chemotherapy INFECTIOUS DISEASES-PHARMACOLOGY & PHARMACY
CiteScore
4.10
自引率
4.50%
发文量
303
审稿时长
47 days
期刊介绍: The Journal of Infection and Chemotherapy (JIC) — official journal of the Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases — welcomes original papers, laboratory or clinical, as well as case reports, notes, committee reports, surveillance and guidelines from all parts of the world on all aspects of chemotherapy, covering the pathogenesis, diagnosis, treatment, and control of infection, including treatment with anticancer drugs. Experimental studies on animal models and pharmacokinetics, and reports on epidemiology and clinical trials are particularly welcome.
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