Modeling and analysis of a human papilloma virus transmission model with impact of media

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-07-03 DOI:10.1016/j.mbs.2024.109247
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引用次数: 0

Abstract

The human papillomavirus (HPV) is threatening human health as it spreads globally in varying degrees. On the other hand, the speed and scope of information transmission continues to increase, as well as the significant increase in the number of HPV-related news reports, it has never been more important to explore the role of media news coverage in the spread and control of the virus. Using a decreasing factor that captures the impact of media on the actions of people, this paper develops a model that characterizes the dynamics of HPV transmission with media impact, vaccination and recovery. We obtain global stability of equilibrium points employing geometric method, and further yield effective methods to contain the HPV pandemic by sensitivity analysis. With the center manifold theory, we show that there is a forward bifurcation when R0=1. Our study suggested that, besides controlling contact between infected and susceptible populations and improving effective vaccine coverage, a better intervention would be to strengthen media coverage. In addition, we demonstrated that contact rate and the effect of media coverage result in multiple epidemics of infection when certain conditions are met, implying that interventions need to be tailored to specific situations.

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受媒体影响的人类乳头瘤病毒传播模型的建模与分析。
人类乳头瘤病毒(HPV)在全球范围内不同程度的传播,威胁着人类的健康。另一方面,随着信息传播速度和范围的不断提高,以及与 HPV 相关的新闻报道数量的大幅增加,探讨媒体新闻报道在病毒传播和控制中的作用变得前所未有的重要。本文利用一个能捕捉媒体对人们行为影响的递减因子,建立了一个模型,描述了 HPV 传播与媒体影响、疫苗接种和恢复的动态关系。我们利用几何方法获得了平衡点的全局稳定性,并通过敏感性分析进一步得出了遏制人乳头瘤病毒大流行的有效方法。利用中心流形理论,我们证明了当 R0=1 时存在正向分叉。我们的研究表明,除了控制感染人群和易感人群之间的接触、提高疫苗的有效覆盖率外,更好的干预措施是加强媒体报道。此外,我们还证明了在满足特定条件时,接触率和媒体覆盖率的影响会导致多重感染流行,这意味着需要根据具体情况采取相应的干预措施。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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