Oncogenic Animal Herpesviruses

IF 5.7 2区 医学 Q1 VIROLOGY Current opinion in virology Pub Date : 2024-07-08 DOI:10.1016/j.coviro.2024.101424
Hafiz S Zafar, Haji Akbar, Huai Xu, Nagendraprabhu Ponnuraj, Kathrine Van Etten, Keith W Jarosinski
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Abstract

Oncogenic viruses play a pivotal role in oncology due to their unique role in unraveling the complexities of cancer development. Understanding the role viruses play in specific cancers is important to provide basic insights into the transformation process, which will help identify potential cellular targets for treatment. This review discusses the diverse role of animal herpesviruses in initiating and promoting various forms of cancer. We will summarize the mechanisms that underlie the development of animal herpesvirus-induced cancer that may provide a basis for developing potential therapeutic interventions or preventative strategies in the future.

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致癌动物疱疹病毒。
致癌病毒在肿瘤学中发挥着举足轻重的作用,因为它们在揭示癌症发展的复杂性方面发挥着独特的作用。了解病毒在特定癌症中扮演的角色非常重要,这将为了解癌症的转化过程提供基础,有助于确定潜在的细胞治疗靶点。本综述将讨论动物疱疹病毒在引发和促进各种癌症中的不同作用。我们将总结动物疱疹病毒诱发癌症的发展机制,为将来开发潜在的治疗干预或预防策略提供依据。
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来源期刊
CiteScore
11.80
自引率
5.10%
发文量
76
审稿时长
83 days
期刊介绍: Current Opinion in Virology (COVIRO) is a systematic review journal that aims to provide specialists with a unique and educational platform to keep up to date with the expanding volume of information published in the field of virology. It publishes 6 issues per year covering the following 11 sections, each of which is reviewed once a year: Emerging viruses: interspecies transmission; Viral immunology; Viral pathogenesis; Preventive and therapeutic vaccines; Antiviral strategies; Virus structure and expression; Animal models for viral diseases; Engineering for viral resistance; Viruses and cancer; Virus vector interactions. There is also a section that changes every year to reflect hot topics in the field.
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