[Renoprotective treatments : renin-angiotensin-aldosterone system blockade and beyond].

La Revue du praticien Pub Date : 2024-06-01
Vincent Esnault
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Abstract

Renoprotective treatments: RENIN-ANGIOTENSINALDOSTERONE SYSTEM BLOCKADE AND BEYOND. Patients with chronic kidney disease (CKD) require both etiological and symptomatic treatments to slow renal function decline. Reductions of protein and salt intakes are required. Pharmacological treatments combines blockade of the renin-angiotensin system, sodium-glucose co-transporter type 2 inhibitors and mineralocorticoid receptor antagonists in most diabetic patients. The albumin creatinine ration (ACR) in morning spot urine samples is now a therapeutic target both in diabetic and non-diabetic CKD patients.

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[肾脏保护疗法:肾素-血管紧张素-醛固酮系统阻断及其他]。
肾脏保护疗法:肾素-血管紧张素-睾酮系统阻断及其他。慢性肾脏病(CKD)患者需要病因治疗和对症治疗,以减缓肾功能衰退。需要减少蛋白质和盐的摄入量。药物治疗包括阻断肾素-血管紧张素系统、钠-葡萄糖共转运体 2 型抑制剂和矿物质皮质激素受体拮抗剂。晨间定点尿样中的白蛋白肌酐比值(ACR)现已成为糖尿病和非糖尿病慢性肾脏病患者的治疗目标。
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